Discrimination of Human Urine from Animal Urine Using 1H-NMR

Journal of Analytical Toxicology
Wonho LeeSuhkmann Kim

Abstract

Urine was most commonly used biological sample in drug test. To create a false-negative test result, some drug abusers were reported to submit animal urine instead of their own. So, the purpose of this study was to compare and differentiate human from animal urine (Rat 370, Pig 12, Horse 10, Cat 8, Dog 13, Cow 10, Monkey 10) samples through the uses of quantitative 1H-NMR and to find biomarkers that can be used for the discrimination of human urine from animal urine. The 1H-NMR spectroscopy was employed and metabolomic analysis with multivariate statistics was carried out. Human urine samples and animal urine samples showed different patterns in metabolites profile and several characteristic metabolites were identified.

References

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Jul 28, 2010·Archives of Pharmacal Research·Young-Shick HongGeum-Sook Hwang
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Feb 24, 2017·Journal of Forensic Sciences·Siwon KimSuhkmann Kim

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Citations

Jan 20, 2020·Metabolomics : Official Journal of the Metabolomic Society·Graciela CarlosPedro Eduardo Fröehlich
Nov 8, 2020·Metabolomics : Official Journal of the Metabolomic Society·Emanuela LocciErnesto d'Aloja
Mar 16, 2021·Journal of Veterinary Pharmacology and Therapeutics·Sol M Rivera-VelezNicolas F Villarino

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