Discriminative behavior and Pavlovian conditioning in the mollusc Pleurobranchaea

Journal of Neurobiology
G J Mpitsos, C S Cohan

Abstract

The buccal motor system in the sea slug Pleurobranchaea californica is multifunctional; similar sets of neurons and muscles generate different behaviors through similar electrophysiological motor patterns. Such multifunctional systems compromise the traditional practice of identifying a motor pattern and then using that pattern to indicate the behavior in reduced preparations. We address this issue in a series of experiments leading to the comparison of differential Pavlovian conditioning in whole animals with the conditioned behavior of the same animals during electrophysiological recording. Because differential conditioning requires two conditioned stimuli (CSs), we show here that each of two CSs activated the conditioned response from animals after they received the stimulus (CS+) paired with an unconditioned stimulus (UCS). Conditioning sessions consisted of 5 training trials with a 2-h intertrial interval. In one study, experimental animals received a 60-s CS+, derived from beer (Sbr), paired with a 50-s electrical shock UCS whose onset occurred 10 s after the CS+ onset; control animals received the Sbr and UCS explicitly unpaired. In a second study, animals received similar procedures as in the first but with a CS+ consis...Continue Reading

References

Feb 3, 1978·Science·G J MpitsosA D McClellan
Jan 1, 1986·Annual Review of Neuroscience·T J Carew, C L Sahley
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan
Mar 1, 1973·Journal of Neurophysiology·G J Mpitosos
Sep 1, 1974·Journal of Neurophysiology·I KupfermannE R Kandel
Oct 29, 1982·Science·E R Kandel, J H Schwartz

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Citations

Dec 1, 1995·Journal of Behavior Therapy and Experimental Psychiatry·W W Tryon
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·G Tesauro
Apr 15, 2011·Journal of Neurophysiology·Liudmila S Yafremava, Rhanor Gillette
Sep 1, 1986·Journal of Neurobiology·G J Mpitsos, C S Cohan
May 11, 2013·The Journal of Experimental Biology·Vanessa Noboa, Rhanor Gillette

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