Disease management at the wildlife-livestock interface: Using whole-genome sequencing to study the role of elk in Mycobacterium bovis transmission in Michigan, USA

Molecular Ecology
Liliana C M SalvadorRowland Kao

Abstract

The role of wildlife in the persistence and spread of livestock diseases is difficult to quantify and control. These difficulties are exacerbated when several wildlife species are potentially involved. Bovine tuberculosis (bTB), caused by Mycobacterium bovis, has experienced an ecological shift in Michigan, with spillover from cattle leading to an endemically infected white-tailed deer (deer) population. It has potentially substantial implications for the health and well-being of both wildlife and livestock and incurs a significant economic cost to industry and government. Deer are known to act as a reservoir of infection, with evidence of M. bovis transmission to sympatric elk and cattle populations. However, the role of elk in the circulation of M. bovis is uncertain; they are few in number, but range further than deer, so may enable long distance spread. Combining Whole Genome Sequences (WGS) for M. bovis isolates from exceptionally well-observed populations of elk, deer and cattle with spatiotemporal locations, we use spatial and Bayesian phylogenetic analyses to show strong spatiotemporal admixture of M. bovis isolates. Clustering of bTB in elk and cattle suggests either intraspecies transmission within the two populations...Continue Reading

References

Oct 1, 1992·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·J C RhyanA J Wilson
Jan 1, 1985·Journal of Molecular Evolution·M HasegawaT Yano
Jan 1, 1983·Comparative Biochemistry and Physiology. A, Comparative Physiology·R D BrownL W Faulkner
Dec 10, 1997·Journal of Wildlife Diseases·S M SchmittJ Sikarskie
Mar 29, 2001·Journal of Wildlife Diseases·C S Bruning-FannD P Muzo
Jun 1, 2002·Journal of Wildlife Diseases·Mitchell V PalmerDiana L Whipple
Jun 14, 2002·Preventive Veterinary Medicine·Daniel J O'BrienJohn B Kaneene
Dec 25, 2002·Emerging Infectious Diseases·Daniel T HaydonM Karen Laurenson
Aug 13, 2003·Journal of Wildlife Diseases·Scott D FitzgeraldWillie M Reed
Jan 17, 2004·Science·Bryan T GrenfellEdward C Holmes
Jan 22, 2004·Bioinformatics·Emmanuel ParadisKorbinian Strimmer
Feb 11, 2005·Molecular Biology and Evolution·A J DrummondO G Pybus
Dec 27, 2005·Veterinary Microbiology·Daniel J O'brienGraham J Hickling
Mar 9, 2006·Systematic Biology·Nicolas Lartillot, Hervé Philippe
May 11, 2006·PLoS Biology·Alexei J DrummondAndrew Rambaut
Nov 13, 2007·BMC Evolutionary Biology·Alexei J Drummond, Andrew Rambaut
Oct 17, 2008·Molecular Biology and Evolution·Cadhla RamsdenMichael A Charleston
Oct 25, 2008·BMC Evolutionary Biology·Joseph Heled, Alexei J Drummond
Oct 30, 2008·Journal of Wildlife Diseases·Daniel J O'BrienJean S Fierke
May 20, 2009·Bioinformatics·Heng Li, Richard Durbin
Jul 1, 2009·Nature Reviews. Genetics·Oliver G Pybus, Andrew Rambaut
Sep 26, 2009·PLoS Computational Biology·Philippe LemeyMarc A Suchard
Oct 3, 2009·Genetics·Erik M VolzSimon D W Frost
Mar 6, 2010·Molecular Biology and Evolution·Philippe LemeyMarc A Suchard
Apr 7, 2010·Molecular Biology and Evolution·Cadhla FirthAndrew Rambaut
Jan 12, 2011·Nature Biotechnology·James T RobinsonJill P Mesirov
Mar 19, 2011·Veterinary Microbiology·Daniel J O'BrienDale E Berry
Jun 15, 2011·The Veterinary Record·Sue Welburn
Aug 23, 2011·Systematic Biology·Joseph Heled, Alexei J Drummond
Aug 1, 2012·Nature Methods·Diego DarribaDavid Posada
Sep 12, 2012·Veterinary Medicine International·Robin A SkuceStanley W J McDowell
Dec 21, 2012·Preventive Veterinary Medicine·Ryan S MillerJennifer L Malmberg
Apr 5, 2013·PLoS Computational Biology·Erik M VolzTrevor Bedford
May 15, 2013·Proceedings of the National Academy of Sciences of the United States of America·Bryony A JonesDirk Udo Pfeiffer
Nov 6, 2013·Transboundary and Emerging Diseases·M V Palmer
Mar 26, 2014·Trends in Microbiology·Rowland R KaoPablo R Murcia
Apr 12, 2014·PLoS Computational Biology·Remco BouckaertAlexei J Drummond

❮ Previous
Next ❯

Citations

Nov 24, 2019·The Veterinary Record·Fabiana Q Mayer, Angélica C Bertagnolli
Mar 27, 2020·Evolution, Medicine, and Public Health·Chloé LoiseauDaniela Brites
Dec 2, 2019·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·R SkuceA Byrne
Apr 14, 2020·Tuberculosis·Michelle H LarsenRichard T Robinson
May 14, 2021·Frontiers in Veterinary Science·Érica Bravo SalesMarcos Bryan Heinemann
May 22, 2021·Microbial Genomics·Rudielle de Arruda RodriguesAndries J van Tonder
May 27, 2021·Trends in Ecology & Evolution·Claire GuinatTanja Stadler
Jul 30, 2021·Frontiers in Veterinary Science·Jason E LombardSuelee Robbe-Austerman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Emerging Infectious Diseases
Lorraine MicheletMaría Laura Boschiroli
The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
H K AdesokanS I B Cadmus
© 2022 Meta ULC. All rights reserved