Disease presentation in relation to infection foci for non-pregnancy-associated human listeriosis in England and Wales, 2001 to 2007.

Journal of Clinical Microbiology
I A GillespieSarah J O'Brien


Listeriosis is a rare but severe food-borne disease, affecting unborn or newly delivered infants, the elderly, and the immunocompromised. The epidemiology of listeriosis in England and Wales changed between 2001 and 2007, with more patients > or = 60 years old presenting with bacteremia (but without central nervous system [CNS] involvement). In order to explain this increase and understand the altered disease presentation, clinical, microbiological, and seasonal data on bacteremic cases of Listeria monocytogenes infection identified through national surveillance were compared with those for patients with CNS infections. Logistic regression analysis was applied while controlling for age. Bacteremic patients, who presented more frequently with gastrointestinal symptoms, were more likely to have underlying medical conditions than CNS patients. This was most marked in patients with malignancies, particularly digestive organ malignancies. Treatment to reduce stomach acid secretion modified the effect of nonmalignant underlying conditions on outcome, i.e., patients with an underlying condition who were not taking acid-suppressing medication were equally likely to have a bacteremic or a CNS infection. However, this type of therapy did...Continue Reading


Sep 28, 1991·BMJ : British Medical Journal·J McLauchlinR J Gilbert
Sep 29, 1988·The New England Journal of Medicine·M J LinnanR Weaver
Feb 17, 1996·BMJ : British Medical Journal·K R NealR F Logan
Jan 1, 1996·Scandinavian Journal of Infectious Diseases·V Goulet, P Marchetti
Apr 27, 2000·The New England Journal of Medicine·P AureliS Salmaso
Jan 11, 2001·The American Journal of Gastroenterology·S Mukherjee
Aug 7, 2004·Journal of Clinical Microbiology·Michel DoumithPaul Martin
Jul 13, 2005·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P Gerner-SmidtB G Bruun
Nov 1, 2006·Emerging Infectious Diseases·Iain A GillespieMartyn Regan
Apr 21, 2007·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C F L AmarJ McLauchlin
Sep 11, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Anna BowenJohn Painter
Apr 29, 2008·Emerging Infectious Diseases·Véronique GouletHenriette de Valk

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