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Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

Jan 20, 2017

Taylor R JayGary E Landreth

Abstract

Neuroinflammation is an important contributor to Alzheimer's disease (AD) pathogenesis, as underscored by the recent identification of immune-related genetic risk factors for AD, including coding variants in the gene TREM2 (triggering receptor expressed on myeloid cells 2). Understandin...read more

Mentioned in this Paper

Study
Familial Alzheimer Disease (FAD)
Pathogenic Aspects
Pathogenesis
APP protein, human
Genes
Brain
Trem2
TREM2 gene
Myeloid Cells
6
7
110
Paper Details
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Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

Jan 20, 2017

Taylor R JayGary E Landreth

PMID: 28100745

DOI: 10.1523/jneurosci.2110-16.2016

Abstract

Neuroinflammation is an important contributor to Alzheimer's disease (AD) pathogenesis, as underscored by the recent identification of immune-related genetic risk factors for AD, including coding variants in the gene TREM2 (triggering receptor expressed on myeloid cells 2). Understandin...read more

Mentioned in this Paper

Study
Familial Alzheimer Disease (FAD)
Pathogenic Aspects
Pathogenesis
APP protein, human
Genes
Brain
Trem2
TREM2 gene
Myeloid Cells
6
7
110

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References
  • Citations26
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations26
123
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