Diseases on hair follicles leading to hair loss part II: scarring alopecias

Skinmed
Katharina WiedemeyerChristoph LOser

Abstract

In Part I of the review (July/August 2004), the anatomy of hair follicles, the diagnostic approach to diseases leading to hair loss, and nonscarring alopecias were discussed. In this article (Part II of II), the focus is on scarring alopecias (dissecting folliculitis, folliculitis decalvans, lichen planopilaris, lupus erythematosus) in regard to pathogenesis, clinical findings, and current options of treatment. Most important for the survival of the hair follicle are the epithelial stem cells within the follicular bulge that communicate with the fibroblasts of the dermal papilla. These structures may be destroyed by systemic autoimmune disorders as well as by granulomatous diseases. To prohibit permanent damage of hair follicles, early diagnosis and the correct treatment are necessary.

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Citations

Sep 26, 2013·Forensic Science, Medicine, and Pathology·Craig James, Neil E I Langlois
Aug 22, 2008·Dermatologic Therapy·Hoon KangJerry Shapiro
Jan 20, 2015·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Alexandros C KatoulisDimitrios Rigopoulos
May 23, 2020·Journal of Cutaneous Pathology·Angel Fernandez-FloresFernando Cabo

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