PMID: 9653511Jul 8, 1998Paper

Disinhibition in the gamma motoneuron circuitry: a neglected mechanism for understanding myofascial pain syndromes?

Applied Psychophysiology and Biofeedback
C C DonaldsonR Schulz

Abstract

Dysregulation in the gamma motoneuron circuitry is proposed as one mechanism to explain the development of trigger point activity in myofascial pain syndrome. Dysregulation in this context is defined operationally as significantly (and functionally) different levels of electrical activity detected in the same muscle on the left and right sides of the body that is persistently present with movement of that muscle. Neurophysiological concepts as they pertain to muscles and motor control principles are reviewed. Research is integrated that ties together material from diverse fields of psychology and medicine. Dysregulation in the gamma motoneuron circuitry may lead to disinhibition of muscle that causes it to remain hyperactive after contraction, generate excessive electrical activity during movement, and/or inappropriately coactivate with other muscles during movement. Any or all of these phenomena may occur with dysregulation. Such dysregulation may be corrected by learning. Immediate clinical implications are discussed, including the addition of specifically targeted neuromuscular retraining procedures via surface electromyography, as well as some conceptual and research issues that require further clarification.

Citations

Oct 27, 2004·American Journal of Physical Medicine & Rehabilitation·Jin Woo ChungW D McCall
Aug 2, 2017·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Fatih AsutayAhmet Hüseyin Acar
Sep 19, 2001·Current Pain and Headache Reports·M H Rivner
Jun 15, 2001·Journal of Clinical Psychology·H H MuellerM Layman
Feb 7, 2003·The Clinical Journal of Pain·Joseph C Arezzo
Jul 18, 2008·International Journal of Oral and Maxillofacial Surgery·Leonidas ManolopoulosThomas P Nikolopoulos

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