PMID: 9640437Jun 26, 1998Paper

Disorders of the sleep-wake cycle in adults

Postgraduate Medical Journal
P M Sedgwick

Abstract

Adults have an intrinsic body clock which regulates a complex series of rhythms including sleep and wakefulness, fatigue and cognitive ability. This endogenous clock naturally runs more slowly than the solar day and is entrained to a 24-h rhythm primarily by the alternation of light and darkness. Jet lag, shift-work sleep disorder, and some of the chronic insomnias are caused by a temporal discrepancy of the body clock relative to the surrounding environment and social network. The underlying mechanisms and general management are described. Both bright light and melatonin therapy have potential in the management of these disorders. Traditionally, bright light therapy has been used to alleviate the depression associated with seasonal affective disorder. Melatonin has received much ill-formed publicity, it being claimed that it is a panacea and an 'antiageing' treatment. Both of these treatment approaches are reviewed.

References

Aug 1, 1979·Pflügers Archiv : European journal of physiology·R A Wever
Oct 1, 1992·Chronobiology International·A J LewyR L Sack
Dec 1, 1992·Journal of Affective Disorders·C I EastmanM A Young
Jan 1, 1991·Experimental Gerontology·C A CzeislerJ F Duffy
May 1, 1986·Electroencephalography and Clinical Neurophysiology·P Lavie
Jan 1, 1982·Neurobiology of Aging·E D WeitzmanJ C Zimmerman
Jul 1, 1981·Archives of General Psychiatry·E D WeitzmanC P Pollak
Jun 1, 1995·Journal of Biological Rhythms·S S CampbellM Terman
Jul 16, 1994·BMJ : British Medical Journal·I HaimovP Lavie
Dec 1, 1993·Archives of General Psychiatry·A Wirz-JusticeW Pöldinger
Aug 1, 1993·Journal of the American Geriatrics Society·S S CampbellM W Anderson
Feb 27, 1993·BMJ : British Medical Journal·J R Stradling
Apr 1, 1993·The American Journal of Psychiatry·A J LevittA Buchanan
May 18, 1996·BMJ : British Medical Journal·M E AttenburrowP J Cowen
Dec 1, 1996·Journal of Sleep Research·L C LackH Wright
Dec 1, 1995·Journal of Sleep Research·J ArendtL Morgan
May 2, 2002·Journal of the American Geriatrics Society·Andrea G SuhnerScott S Campbell

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Citations

Feb 20, 1999·Journal of Women's Health
May 26, 2005·Journal of Interpersonal Violence·Carol VanZile-TamsenJennifer A Livingston
Nov 1, 2005·Journal of Research on Adolescence : the Official Journal of the Society for Research on Adolescence·Yoonsun ChoiRichard F Catalano
Oct 19, 2005·Brain : a Journal of Neurology·I ArnulfE Mignot
May 7, 2016·The Cochrane Database of Systematic Reviews·Marcio M de OliveiraGilmar F Prado
Sep 10, 2003·Neuroreport·Hirofumi MikiMorito Monden
Nov 3, 2007·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Marita FouladiunKent Lundholm

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