Disparity-selective neurons in area V4 of macaque monkeys

Journal of Neurophysiology
Masayuki WatanabeI Fujita

Abstract

Area V4 is an intermediate stage of the ventral visual pathway providing major input to the final stages in the inferior temporal cortex (IT). This pathway is involved in the processing of shape, color, and texture. IT neurons are also sensitive to horizontal binocular disparity, suggesting that binocular disparity is processed along the ventral visual pathway. In the present study, we examined the processing of binocular disparity information by V4 neurons. We recorded responses of V4 neurons to binocularly disparate stimuli. A population of V4 neurons modified their responses according to changes of stimulus disparity; neither monocular responses nor eye movements could account for this modulation. Disparity-tuning curves were similar for different locations within a neuron's receptive field. Neighboring neurons recorded using a single electrode displayed similar disparity-tuning properties. These findings indicate that a population of V4 neurons is selective for binocular disparity, invariant for the position of the stimulus within the receptive field. The finding that V4 neurons with similar disparity selectivity are clustered suggests the existence of functional modules for disparity processing in V4.

References

Jun 4, 1979·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A Cowey, J Porter
Jan 1, 1991·Cerebral Cortex·D J Felleman, D C Van Essen
Jul 1, 1991·Journal of Neurophysiology·K TanakaM Moriya
Mar 1, 1987·Journal of Neurophysiology·R Desimone, S J Schein
Apr 1, 1987·Journal of Neurophysiology·D J Felleman, D C Van Essen
Jan 1, 1972·Journal of Neurophysiology·C G GrossD B Bender
Feb 1, 1972·American Journal of Ophthalmology·T B Rothstein, J G Sacks
Feb 17, 1980·Brain Research·R DesimoneC G Gross
Jun 1, 1983·Brain : a Journal of Neurology·J ZihlN Mai
Jan 1, 1981·Experimental Brain Research·A F Dean
Sep 8, 1994·Nature·E A DeYoeE McClendon
May 1, 1993·The European Journal of Neuroscience·E Peterhans, R von der Heydt
Jan 1, 1993·Visual Neuroscience·R DesimoneM Mishkin
Apr 1, 1997·Journal of Neurophysiology·G M Ghose, D Y Ts'o
Jun 1, 1997·Journal of Neurophysiology·I OhzawaR D Freeman
Aug 26, 1998·Nature·G C DeAngelisW T Newsome
Aug 13, 1999·Journal of Neurophysiology·A AnzaiR D Freeman
Aug 13, 1999·Journal of Neurophysiology·A AnzaiR D Freeman
Aug 13, 1999·Journal of Neurophysiology·A AnzaiR D Freeman
Nov 24, 1999·Journal of Neurophysiology·S Eifuku, R H Wurtz
Jul 19, 2000·Journal of Neurophysiology·T UkaI Fujita
Sep 14, 2000·Neuron·P JanssenG A Orban
Feb 13, 2001·Journal of Neurophysiology·H TanakaI Fujita
Apr 3, 2001·Annual Review of Neuroscience·B G Cumming, G C DeAngelis

Citations

Oct 7, 2008·Nature Neuroscience·Yukako YamaneCharles E Connor
Apr 9, 2009·Nature Reviews. Neuroscience·Jonathan J Nassi, Edward M Callaway
Dec 2, 2009·BMC Neuroscience·Fabrice ArcizetPascal Girard
Jul 15, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·A AnzaiG C DeAngelis
Aug 26, 2014·Frontiers in Integrative Neuroscience·Olivier Joly, Edit Frankó
Jun 9, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Bram-Ernst VerhoefPeter Janssen
Jun 9, 2016·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·I Fujita, Takahiro Doi
Aug 23, 2016·Frontiers in Systems Neuroscience·Ivan N Pigarev, Ekaterina V Levichkina
Jul 18, 2006·Trends in Neurosciences·G A OrbanR Vogels
Jun 2, 2009·Brain Research Reviews·Reza Farivar
Dec 24, 2014·Proceedings of the National Academy of Sciences of the United States of America·Gouki OkazawaHidehiko Komatsu
Feb 16, 2005·Neuroscience Research·Ken-Ichiro TsutsuiH Sakata
Jun 28, 2005·Vision Research·Sieu K Khuu, Anthony Hayes
Oct 26, 2012·Perception·Katalin MarkóGábor Jandó
Sep 11, 2014·Vision Research·Elena GheorghiuNicolai Petkov
Apr 20, 2004·Neuroreport·Roland Marcus Rutschmann, Mark W Greenlee
May 3, 2005·Nature Neuroscience·Andrew E WelchmanZoe Kourtzi
Aug 28, 2004·Journal of Neurophysiology·Peter NeriDavid J Heeger
Sep 3, 2004·Journal of Neurophysiology·Jay Hegdé, D C Van Essen
Jul 25, 2015·Science Advances·William W SpragueMartin S Banks
Jan 13, 2018·Cerebral Cortex·Yang FangHaidong D Lu
Jul 1, 2005·Journal of Neurophysiology·David A Hinkle, Charles E Connor
Jul 1, 2005·Journal of Neurophysiology·Jay Hegdé, D C Van Essen
Jun 18, 2002·Nature Neuroscience·David A Hinkle, Charles E Connor
Feb 8, 2003·Journal of Neurophysiology·G C DeAngelis, Takanori Uka
Dec 8, 2006·Journal of Neurophysiology·Chandramouli ChandrasekaranAndrew E Welchman
May 18, 2007·Journal of Neurophysiology·Kazumasa UmedaI Fujita
Jan 16, 2008·Physiological Reviews·G A Orban
Oct 26, 2007·Journal of Neurophysiology·Hironori KumanoI Fujita
Jun 26, 2020·Annual Review of Vision Science·Anitha PasupathyTaekjun Kim
Dec 7, 2018·Eye·Serdar OzatesPelin Yilmazbas
Apr 17, 2009·Journal of Neurophysiology·Yasuyo KotakeHiroshi Tamura
Apr 1, 2020·Cerebral Cortex·Yseult Héjja-BrichardBenoit R Cottereau
Oct 24, 2020·Current Biology : CB·Ramanujan SrinathKristina J Nielsen

Related Concepts

Cell Aggregation
Depth Perception
Discrimination (Process of Differentiation)
Electrophysiology (Science)
Macaca
Afferent Neuron
Photic Stimulation
Optic Tract Structure
Vision, Binocular
Vision, Monocular

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