Dissecting folliculitis (dissecting cellulitis) of the scalp: a 66-patient case series and proposal of classification

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
Chaw-Ning LeeChao-Chun Yang

Abstract

Dissecting folliculitis (DF) or dissecting cellulitis of the scalp is regarded as a rare disease with disfiguring scarring alopecia. This study aimed to analyze the features of DF and to propose a classification to define its severity. A hospital-based retrospective study was conducted. Patients with a histopathological diagnosis or clinical features leading to diagnosis of DF were included and classified into three stages. Among the 66 patients recruited (63 men / 3 women, mean age 24.9 years), multiple interconnected alopecic nodules involving the vertex scalp were the main feature. Histopathology showed an extensive inflamed granulation abscess forming a dissection plane in the lower dermis/subcutis in the acute stage. Lymphocytic infiltration was predominant in seven of 21 histology specimens. Overweight and obesity were noted in 29 of 45 patients examined. No association with smoking was found. There was comorbidity with acne conglobata in 15 of 66 patients, two of whom had acne inversa. Longer disease duration and greater number of nodules were associated with higher severity of DF (p < 0.05). A complete remission rate of 25 % was achieved by any treatment, and a rate of 37.5 % was achieved with oral isotretinoin alone. D...Continue Reading

References

Apr 12, 2001·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·M L Beehner
Jan 11, 2003·Journal of the American Academy of Dermatology·Elise A OlsenUNKNOWN Workshop on Cicatricial Alopecia
Dec 18, 2003·The Journal of Clinical Investigation·Kathryn E Wellen, Gokhan S Hotamisligil
Jan 17, 2013·The British Journal of Dermatology·F W DanbyM von Laffert
Jul 19, 2014·Indian Journal of Dermatology, Venereology and Leprology·Shiling QiXingqi Zhang
Sep 12, 2014·Annales de dermatologie et de vénéréologie·C KoudoukpoH Yédomon
Apr 23, 2015·The Journal of Dermatology·Ichiro KurokawaUNKNOWN Japan Acne Research Society
Jul 3, 2015·The British Journal of Dermatology·A BadaouiV Descamps
Dec 1, 2015·Dermatologic Clinics·Ioannis KaragiannidisChristos C Zouboulis
Aug 26, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·G Segurado-MiravallesS Vañó-Galván

❮ Previous
Next ❯

Citations

Apr 15, 2020·Dermatologic Therapy·Francisco José Navarro-TriviñoRicardo Ruiz-Villaverde
Dec 9, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·A AlessandriniM Starace
May 29, 2021·Photodiagnosis and Photodynamic Therapy·Lun YangAiyuan Guo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cellulitis

Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. Discover the latest research on cellulitis here.

Related Papers

Journal of the European Academy of Dermatology and Venereology : JEADV
A KhaledM R Kamoun
Dermatology : International Journal for Clinical and Investigative Dermatology
V De FrancescoM Campanella
© 2022 Meta ULC. All rights reserved