Disseminate fungal infection after acute pancreatitis in a simultaneous pancreas-kidney recipient.

Journal of Transplantation
Anna RossettoGian Luigi Adani

Abstract

Fungal infections after kidney transplantation are a major cause of morbidity and mortality, and Candida infection of the pancreas is considered an infrequent but important agent in necrotizing pancreatitis. We report the case of a 43-year-old Caucasian patient who underwent simultaneous pancreas-kidney transplantation because of diabetes type I, and chronic renal failure with peritoneal dialysis. The postoperative course was complicated by acute pancreatitis due to the thrombosis of the splenic artery of the graft, the subsequent acute rupture of the external iliac artery caused by fungal arteritis (Candida glabrata), and peritonitis a few days later caused by sigmoid perforation with detection of Candida glabrata infection of the resected intestinal tract. The present case remarks that awareness and prevention of fungal infection are major issues in the transplant field. Important information can be added by systematic culture of conservation perfusates but, probably, the best way for early recognition of a critical level of infectious risk remains the routine application of the colonization index screening. In cases of positive results, preemptive antifungal therapy could be warranted.

References

Jun 12, 1998·The New England Journal of Medicine·J A Fishman, R H Rubin
May 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·O UzunJ H Rex
Jan 17, 2002·Transplant International : Official Journal of the European Society for Organ Transplantation·A ChkhotuaE Mor
Jul 17, 2003·Transplantation·Umberto BaccaraniGiuseppe Mioni
Dec 31, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter G PappasUNKNOWN Infectious Diseases Society of America
May 25, 2005·Transplant International : Official Journal of the European Society for Organ Transplantation·Claudio Ponticelli, Patrizia Passerini
Mar 8, 2007·Surgery Today·Arunaloke ChakrabartiJaidev Wig
Dec 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Laetitia AlbanoUNKNOWN French Mycosis Study Group
May 23, 2009·Transplantation Proceedings·F CoccoliniA D Pinna

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Citations

Jul 11, 2013·Nephro-urology Monthly·Mohammad Ali AfshariBehzad Einollahi
Sep 25, 2017·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Maozhi TangHong Liu
Dec 21, 2012·Current Opinion in Organ Transplantation·Silvio NadalinAlfred Königsrainer
Feb 7, 2020·Transplant International : Official Journal of the European Society for Organ Transplantation·Franka MessnerChristian Margreiter

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