Disseminated Cladophialophora bantiana infection in a heart transplant recipient

The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Andreas KeyserDietrich E Birnbaum

Abstract

Cerebral phaeohyphomycosis caused by Cladophialophora bantiana, a dematiaceous fungus, is a rare disease. The majority of cases have been reported among immunocompetent patients; only 4 cases have been published that describe transplantation patients. The overall prognosis is poor. Surgical therapy in combination with chemotherapy with itraconazole is recommended. We report the case of a heart transplant recipient with cutaneous, cerebral, and lung manifestation of Cladophialophora bantiana who died despite surgical and systemic, high-dosage itraconazole treatment.

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Citations

May 19, 2007·Medical Mycology·Fernanda P Silveira, Shahid Husain
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