Disseminated fungal infection in a renal transplant recipient involving Macrophomina phaseolina and Scytalidium dimidiatum: case report and review of taxonomic changes among medically important members of the Botryosphaeriaceae

Medical Mycology
Darrell H S TanIgnatius W Fong

Abstract

We report the first case of human infection with the fungal plant pathogen Macrophomina phaseolina in a Sri Lankan-born Canadian man following a renal transplant in India. The patient subsequently succumbed to invasive infection with Scytalidium dimidiatum. Molecular sequence analysis confirmed the identification of both fungi and revealed that they are related species within the ascomycete family Botryosphaeriaceae. We review the rationale for the recent reclassification of S. dimidiatum as Neoscytalidium dimidiatum and of Nattrassia mangiferae (formerly considered a synanamorph of S. dimidiatum) as Neofusicoccum mangiferae. This and other recent cases illustrate the potential for plant pathogenic fungi to cause invasive human diseases which are refractory to antifungal therapy.

References

Jul 1, 1991·Archives of Dermatology·B E Elewski, D L Greer
Feb 1, 1981·The American Journal of Medicine·R H RubinN E Tolkoff-Rubin
Jan 1, 1994·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M E Levi, J W Smith
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Jun 4, 1998·Mycoses·C A Oycka, H C Gugnani
Apr 20, 2002·Current Opinion in Infectious Diseases·Roderick J Hay
May 10, 2002·Mycoses·Tawanda GumboPraise Masvaire
Aug 24, 2002·Médecine tropicale : revue du Corps de santé colonial·J Maslin, J J Morand
Jan 22, 2003·The British Journal of Dermatology·S AamirT Haroon
Jun 6, 2003·Journal of the American Academy of Dermatology·Claire LacroixMartine Feuilhade de Chauvin
Jul 12, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shahid HusainNina Singh
Dec 10, 2003·Journal of Clinical Microbiology·James J DunnKaren C Carroll
Jan 13, 2004·Journal of Clinical Microbiology·Birgit WillingerStefan Winkler
Jan 16, 2004·Clinical and Experimental Dermatology·R UngpakornS Reangchainam
Feb 18, 2004·Journal of Cataract and Refractive Surgery·Mahmood JabbarvandAli Amini
Jan 22, 2005·The Veterinary Record·T HasegawaK Takatori
May 3, 2005·Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·Rataporn Ungpakorn
Sep 15, 2005·Phytotherapy Research : PTR·Jehan AraViqar Uddin Ahmad
Feb 24, 2007·International Ophthalmology·Ali Sadeghi TariZohreh Abedinifar

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Citations

May 10, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P AroraA Chaudhury
Oct 12, 2010·Clinical Microbiology Reviews·Sanjay G Revankar, Deanna A Sutton
Feb 6, 2009·Journal of Clinical Microbiology·Hila ElinavMaya Korem
Apr 24, 2009·Journal of Clinical Microbiology·Ashok SrinivasanJerry L Shenep
Jan 9, 2010·Medical Mycology·Mery Ruíz-CendoyaJosep Guarro
Oct 3, 2014·The Journal of Laryngology and Otology·A HaririH A Saleh
Jan 1, 2012·Medical Mycology Case Reports·T PremamaliniAnupma J Kindo
May 27, 2009·The Lancet Infectious Diseases·Dong Ming Li, G Sybren de Hoog
Jan 20, 2012·Critical Reviews in Microbiology·Surinder KaurVijay Bahadur Chauhan
Feb 19, 2013·Journal de mycologie médicale·M MachouartN Desbois
Feb 4, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A ChowdharyM Cuenca-Estrella
Apr 26, 2018·Mycoses·Nicomedes Valenzuela-LopezJosep Guarro
May 8, 2015·Journal of Clinical Microbiology·Brandon DionneBernadette Jakeman
Sep 7, 2018·Mycoses·Rosa Paulina Calvillo-MedinaVictor Manuel Bautista-de Lucio
Nov 16, 2019·International Journal of Dermatology·Robert A Schwartz, Rajendra Kapila
Oct 17, 2020·Annals of Laboratory Medicine·Su Yeon JoJongyoun Yi
Jan 29, 2021·Frontiers in Cellular and Infection Microbiology·Ganeshamoorthy Hariharan, Kandeeparoopan Prasannath

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