PMID: 696312Sep 1, 1978Paper

Disseminated Herpes simplex virus infection in ataxia-telangiectasia

Acta paediatrica Scandinavica
A Ben-ZviS Yatziv

Abstract

The clinical and pathological features are described in a child with ataxia-telangiectasia, complicated by fatal disseminated herpes simplex virus infection. Herpes simplex virus was isolated from the patient's blood, and the histopathological findings in the skin, liver and adrenals were consistent with herpes simplex virus infection. The patient had a combined immune deficiency state, as a part of the ataxia-telangiectasia syndrome. She had imparied cellular immune response to herpes simplex virus and developed no antibodies against the virus. To our knowledge, this is the first fatal case of disseminated herpes simplex virus infection in ataxiatelangiectasia.

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Citations

Apr 1, 1985·Journal of the American Academy of Dermatology·L L Smith, S L Conerly
Sep 15, 2000·Infectious Disease Clinics of North America·J D Fingeroth
Sep 10, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Liora HarelJacob Amir
Dec 4, 2009·Journal of Pediatric Hematology/oncology·Dirk HolzingerAndreas H Groll
Apr 8, 2004·The Journal of Pediatrics·Anna Nowak-WegrzynHoward M Lederman

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