Disseminated Histoplasmosis as AIDS-presentation. Case Report and Comprehensive Review of Current Literature

Mediterranean Journal of Hematology and Infectious Diseases
Paola ZanottiEmanuele Focà

Abstract

Progressive disseminated histoplasmosis (PDH) is an AIDS-defining illness with a high lethality rate if not promptly treated. The wide range of its possible clinical manifestations represents the main barrier to diagnosis in non-endemic countries. Here we present a case of PDH with haemophagocytic syndrome in a newly diagnosed HIV patient and a comprehensive review of disseminated histoplasmosis focused on epidemiology, clinical features, diagnostic tools and treatment options in HIV-infected patients.

Citations

Sep 6, 2019·Clinical Journal of Gastroenterology·Mathew FinnissParas Patel
Dec 13, 2019·Case Reports in Infectious Diseases·Chiara PapaliniMaria Bruna Pasticci
Oct 30, 2020·Drug Discoveries & Therapeutics·Farhan FazalAnimesh Ray
Dec 20, 2020·Hematology, Transfusion and Cell Therapy·Naseelah Yunus MussáDinah Carvalho

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Methods Mentioned

BETA
biopsy
biopsies
bronchoalveolar
enzyme-linked immunosorbent assay
bronchoalveolar lavage
PCR

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