Disseminated infection by Bipolaris spicifera in an immunocompetent subject

Medical Mycology
Hiromi KobayashiShinichiro Hayashi

Abstract

We report a case of disseminated infection due to Bipolaris spicifera in an immunocompetent male. Histopathological studies of lymph node, lung, and liver biopsy specimens showed a dark pigmented, granular fungal structure inside the granuloma. The disease was accompanied by the unusual feature of positive lupus anticoagulant in serum and low-density areas expanding along the portal vein in the liver. The disease responded to combination therapy with intravenous amphotericin B and voriconazole, but recurred during oral itraconazole. The fungal isolate from the lymph node was identified as Bipolaris spicifera on the basis of morphology and molecular biological data.

Citations

Oct 12, 2010·Clinical Microbiology Reviews·Sanjay G Revankar, Deanna A Sutton
Feb 27, 2013·Mycoses·Katihuska ParedesJosep Guarro
Feb 18, 2011·Transplant Infectious Disease : an Official Journal of the Transplantation Society·L RosowS Kesari
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Jun 19, 2014·Diagnostic Microbiology and Infectious Disease·Katihuska ParedesJosep Guarro
Nov 3, 2017·Frontiers in Immunology·Eszter Judit TóthTamás Papp
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