Disseminated Mycobacterium genavense infection in a FIV-positive cat

Journal of Feline Medicine and Surgery
M S HughesRichard Malik

Abstract

An 8-year-old FIV-positive Australian cat was presented with coughing, periocular alopecia, pyrexia and inappetence. Skin scrapings demonstrated Demodex cati mites. Antibiotics were administered and it was treated successfully for periocular demodectic mange, but the cat continued to exhibit respiratory signs and lose weight. Further investigation revealed an ascarid infection and active chronic inflammation of undetected cause affecting the lower airways. Repetitive treatment with pyrantel failed to eradicate the ascarid infection. The cat became cachectic and developed moist ulcerative dermatitis of the neck, severe non-regenerative anaemia, leucopenia and thrombocytopenia. Necropsy and histopathology revealed mycobacteriosis affecting skin, lungs, spleen, lymph nodes, liver and kidney. Attempted culture of frozen tissues at a mycobacteria reference laboratory was unsuccessful. Paraffin-embedded, formalin-fixed tissue was retrieved and examined using PCR to amplify part of the 16S rRNA gene. A diagnosis of disseminated Mycobacterium genavense infection was made based on the presence of acid fast bacteria in many tissues and partial sequence of the 16S rRNA gene. Although M genavense has been identified previously as a cause o...Continue Reading

References

Nov 1, 1992·Journal of Clinical Microbiology·K JacksonB Dwyer
Dec 1, 1992·Journal of Clinical Microbiology·M B CoyleE C Böttger
Jan 1, 1991·Biomaterials, Artificial Cells, and Immobilization Biotechnology : Official Journal of the International Society for Artificial Cells and Immobilization Biotechnology·M Nishimura
Dec 6, 1990·The New England Journal of Medicine·B I Eisenstein
Sep 1, 1990·Journal of General Microbiology·T RogallE C Böttger
Jan 1, 1986·American Journal of Clinical Pathology·D C FarhiC R Horsburgh
Jun 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P Matsiota-BernardC Nauciel
Nov 1, 1994·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E C Böttger
Aug 1, 1994·Journal of Clinical Microbiology·M S HughesR A Skuce
Oct 1, 1993·International Journal of Systematic Bacteriology·E C BöttgerM B Coyle
Jan 1, 1994·American Journal of Clinical Pathology·H MaschekE C Böttger
Jan 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D NadalU B Schaad
Apr 1, 1993·Journal of Clinical Microbiology·R K HoopM Salfinger
May 1, 1996·Journal of Clinical Microbiology·G MangiapanA J Hance
Jul 1, 1996·Journal of Clinical Microbiology·T E KiehnD Armstrong
Feb 1, 1996·Journal of Clinical Microbiology·F PortaelsW de Meurichy
Apr 1, 1996·Journal of Clinical Microbiology·R K HoopG E Pfyffer
Oct 8, 1997·Journal of Clinical Microbiology·M S HughesS D Neill

❮ Previous
Next ❯

Citations

Oct 27, 2017·Journal of Feline Medicine and Surgery·Katherine Backel, Christine Cain
Sep 12, 2018·Journal of Avian Medicine and Surgery·Anna SchmitzRüdiger Korbel
Nov 27, 2018·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Bérengère DequéantEdouard Reyes-Gomez
Jan 29, 2011·The Journal of Obstetrics and Gynaecology Research·Vladimira SadlonovaJurina Sadlonova
Feb 28, 2018·Assistive Technology : the Official Journal of RESNA·Mohammad KhodadadiHassan Zohoor
Jul 22, 2004·Journal of Feline Medicine and Surgery·M S HughesR Malik
Jun 2, 2009·Journal of Feline Medicine and Surgery·Margaret J HosieMarian C Horzinek
Oct 18, 2005·Journal of Feline Medicine and Surgery·Randolph M BaralRichard Malik
Feb 16, 2007·Australian Veterinary Journal·M J Hosie, J A Beatty
Jul 29, 2010·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J S Doggett, L Strasfeld
Nov 13, 2012·Veterinary Dermatology·Bronwyn SmitsJanet A Fyfe
Apr 26, 2011·Journal of Feline Medicine and Surgery·Susan F Foster, Patricia Martin
Jul 3, 2013·Journal of Feline Medicine and Surgery·Albert LloretMarian C Horzinek
Jun 10, 2015·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Kathleen M KellyRichard J Montali
Apr 21, 2018·Viruses·Craig MillerSue VandeWoude
Jun 27, 2019·Journal of Feline Medicine and Surgery·Sarah Winzelberg Olson, Ann E Hohenhaus
Dec 1, 2000·Australian Veterinary Journal·J LucasR Malik
Mar 1, 2002·Journal of Feline Medicine and Surgery·R MalikD N Love
Apr 3, 2014·Pathology Research International·M SantosM Gobernado
Jan 8, 2021·Frontiers in Genetics·Alexander Stephen ByrneKapil Tahlan

❮ Previous
Next ❯

Datasets Mentioned

BETA
X60070

Methods Mentioned

BETA
PCR
scrapings
electrophoresis
bronchoalveolar
lavage
bone marrow aspiration
biopsy

Software Mentioned

DNASIS

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Cachexia & Brown Fat

Cachexia is a condition associated with progressive weight loss due to severe illness. In cancer patients, it is proposed to occur as a result of tumor-induced energy wasting. Several proteins have been implicated in browning and depletion of white adipose tissue. Here is the latest research on cachexia and brown fat.

Cardiac Cachexia

Cardiac cachexia is a syndrome associated with the progressive loss of muscle and fat mass. It most commonly affects patients with heart failure and can significantly decrease the quality of life and survival in these patients. Here is the latest research on cardiac cachexia.