Dissemination amongst humans and food products of animal origin of a Salmonella typhimurium clone expressing an integron-borne OXA-30 beta-lactamase

The Journal of Antimicrobial Chemotherapy
Patrícia AntunesLuísa Peixe

Abstract

Characterization of the molecular basis for beta-lactam resistance and evaluation of the clonal relatedness among nine isolates of multidrug-resistant Salmonella typhimurium recovered from seven clinical human samples and two pork end products. The isolates were examined for susceptibility to antimicrobial agents. The relationships between resistance genes, class 1 integrons, plasmids and isolates were screened by molecular methods such as polymerase chain reaction and restriction fragment length analysis. A bla(OXA-30) gene, located in a class 1 integron, was detected in all isolates. This integron was present on a conjugative plasmid in all but one isolate. By pulsed-field gel electrophoresis, it was determined that all strains share the same chromosomal type. This study demonstrates the spread of an OXA-30-producing S. typhimurium in Portugal, suggesting dissemination of a resistant clone through the food chain.

Citations

May 16, 2009·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A HerreroM R Rodicio
Jan 17, 2013·Foodborne Pathogens and Disease·Marcus Ho Yin WongSheng Chen
Sep 2, 2009·Antimicrobial Agents and Chemotherapy·Laurent PoirelPatrice Nordmann
Aug 23, 2011·Applied and Environmental Microbiology·Maria KarczmarczykSéamus Fanning
Mar 7, 2006·Journal of Clinical Microbiology·François-Xavier WeillPatrick A D Grimont
Aug 26, 2014·Jundishapur Journal of Microbiology·Fariba AsgharpourZahra Moulana
Feb 19, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·K M OsmanR A H Mohamed
Jul 4, 2006·International Journal of Food Microbiology·Bojana Beović
Apr 4, 2013·Mobile Genetic Elements·Sara DominguesKaare M Nielsen
Feb 17, 2009·Enfermedades infecciosas y microbiología clínica·María Del Carmen MendozaMaría Rosario Rodicio
Feb 20, 2007·Veterinary Microbiology·Xian-Zhi LiLateef Adewoye
Apr 5, 2013·Clinical Microbiology Reviews·Anna Fàbrega, Jordi Vila
Jun 16, 2005·Expert Review of Anti-infective Therapy·Miranda BatchelorErnesto Liebana
Mar 29, 2007·Journal of Food Protection·Samuel D AlcaineMartin Wiedmann
May 24, 2006·Microbes and Infection·Geovana Brenner MichaelStefan Schwarz
Sep 28, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P AntunesL Peixe

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.