Dissociated effects of anticipating smoking versus monetary reward in the caudate as a function of smoking abstinence

Biological Psychiatry
Maggie M SweitzerEric C Donny

Abstract

Theories of addiction suggest that chronic smoking may be associated with both hypersensitivity to smoking and related cues and hyposensitivity to alternative reinforcers. However, neural responses to smoking and nonsmoking rewards are rarely evaluated within the same paradigm, leaving the extent to which both processes operate simultaneously uncertain. Behavioral evidence and theoretical models suggest that dysregulated reward processing may be more pronounced during deprivation from nicotine, but neuroimaging evidence on the effects of deprivation on reward processing is limited. The current study examined the impact of deprivation from smoking on neural processing of both smoking and monetary rewards. Two separate functional magnetic resonance imaging scans were performed in 38 daily smokers, one after smoking without restriction and one following 24 hours of abstinence. A rewarded guessing task was conducted during each scan to evaluate striatal blood oxygen level-dependent response during anticipation of both smoking and monetary rewards. A significant reward type by abstinence interaction was observed in the bilateral caudate and medial prefrontal cortex during reward anticipation. The blood oxygen level-dependent respons...Continue Reading

References

Mar 1, 1986·Archives of General Psychiatry·J R Hughes, D Hatsukami
Feb 1, 1983·Behavioural Brain Research·E T RollsS P Maddison
Sep 1, 1993·Brain Research. Brain Research Reviews·T E Robinson, K C Berridge
Aug 1, 1995·Psychopharmacology·K J Schuh, M L Stitzer
Mar 1, 1995·NeuroImage·K J FristonR Turner
Sep 1, 1995·NeuroImage·K J Worsley, K J Friston
May 20, 1998·Nature·M P Epping-JordanA Markou
Nov 4, 2000·The American Journal of Psychiatry·H GaravanE A Stein
Dec 9, 2000·Journal of Neurophysiology·M R DelgadoJ A Fiez
Nov 13, 2001·The European Journal of Neuroscience·C Martin-SoelchK L Leenders
Oct 17, 2002·European Psychiatry : the Journal of the Association of European Psychiatrists·J WraseA Heinz
Apr 24, 2003·Behavioral Neuroscience·Joyce Besheer, Rick A Bevins
Aug 13, 2003·The European Journal of Neuroscience·C Martin-SoelchW Schultz
Mar 6, 2004·Nature Neuroscience·Stephen J WilsonJulie A Fiez
Apr 17, 2004·Science·John O'DohertyRaymond J Dolan
Oct 7, 2004·The American Journal of Psychiatry·Andreas HeinzPeter Bartenstein
May 28, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·F Joseph McClernonJed E Rose
Aug 9, 2005·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Stephen J WilsonJulie A Fiez
Sep 30, 2005·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Paul J Kenny, Athina Markou
Oct 18, 2005·Addictive Behaviors·Benjamin A TollSherry A McKee
Oct 28, 2005·Nature Neuroscience·George F Koob, Michel Le Moal
Apr 7, 2006·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Dharma McBrideAlain Dagher
Apr 26, 2006·NeuroImage·K J FristonR N Henson
Dec 22, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ahmad R HaririStephen B Manuck
Mar 22, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Teresa R FranklinAnna Rose Childress
May 21, 2008·Journal of Abnormal Psychology·Stephen J WilsonJulie A Fiez
Jul 26, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·George F Koob, Michel Le Moal
Oct 1, 2008·Drug and Alcohol Dependence·Fleur ZijlstraIngmar H A Franken
Dec 3, 2008·The American Journal of Psychiatry·Erika E ForbesRonald E Dahl
Feb 3, 2009·Handbook of Experimental Pharmacology·Allen AzizianEdythe D London
Feb 19, 2009·Psychopharmacology·Kenneth J ThielJanet L Neisewander
Feb 28, 2009·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Angela S AttwoodMarcus R Munafò
May 8, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Rita Z GoldsteinNora D Volkow

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Citations

Jan 31, 2016·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Menton M DeweeseFrancesco Versace
Feb 5, 2016·Brain Imaging and Behavior·Yanzhi BiJie Tian
Dec 30, 2014·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·David M LydonCharles F Geier
Jul 16, 2014·Neuroscience and Biobehavioral Reviews·David M LydonCharles F Geier
Apr 20, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Maggie M SweitzerEric C Donny
Jul 16, 2014·Behavior Therapy·Gabrielle I LiverantGary B Kaplan
Apr 4, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Jason A OliverDavid J Drobes
Nov 9, 2017·Substance Use & Misuse·Charles GeierDavid Lydon-Staley
May 10, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·John R HughesJeff Priest
Aug 6, 2020·Frontiers in Psychiatry·Ting XueKai Yuan
May 10, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Nicolas J Schlienz, Larry W Hawk
Apr 24, 2015·Addiction Biology·Francis Joseph McClernonDana M Van Wert
Nov 13, 2021·NeuroImage. Clinical·Priyamvada ModakJoshua W Brown

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