Dissociation of field potential from neuronal activity in the isolated retina: failure of the b-wave with normal ganglion cell response.

Journal of Neurobiology
R H Masland, A Ames

Abstract

The b-wave of the isolated rabbit retina was compared with the ganglion cell response to light before and after modification of the retina's incubating medium. Marked diminution of the b-wave, with no reduction in ganglion cell response, was observed under three experimental conditions: (1) following a short period of anoxia; (2) following a short period in 0.2 mM Ca++; (3) in a small percentage of preparations, simply as a result of prolonged incubation in control medium. In contrast, a short period in 50 mM K+ led to a parallel fall and parallel recovery of both responses. It is apparent that under selected conditions the field potentials which constitute the b-wave are poorly correlated with the retina's neural activity.

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Citations

Nov 1, 1990·Documenta Ophthalmologica. Advances in Ophthalmology·J C HuangC M Kemp
Sep 25, 1981·Molecular and Cellular Biochemistry·J Y WuD M Lam
Jan 1, 1990·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·R A Linsenmeier
Jul 28, 1978·Brain Research·D R Pepperberg, R H Masland
Jan 14, 2000·Journal of Neuroscience Methods·E A Newman, R Bartosch
Apr 5, 2001·Progress in Retinal and Eye Research·G Niemeyer
Mar 1, 1997·Visual Neuroscience·M A McRipleyR A Linsenmeier
Jul 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·C BrandonJ Y Wu
Oct 1, 1981·Journal of Neurochemistry·A Ames, F B Nesbett
May 15, 2012·Progress in Retinal and Eye Research·Wallace B Thoreson, Stuart C Mangel
Apr 9, 2016·Neuropharmacology·Puneet Sodhi, Andrew T E Hartwick
Oct 1, 1977·The Journal of Comparative Neurology·R H Masland

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