PMID: 6107338Oct 1, 1980Paper

Dissolution rates of sulfamethoxazole utilizing sugar glass dispersions

The Journal of Pharmacy and Pharmacology
A GhanemY Ibraheem

Abstract

Solid glass dispersions of sulfamethoxazole have been prepared by fusion using different classes of sugars, A marked increase in the dissolution rate of sulfamethoxazole in the solid dispersions was observed compared with that of the drug alone. During the fusion process, interaction took place between sulfamethoxazole and those sugars with carbonyl groups. The bacteriological activity of sulfamethoxazole was not changed by the interaction compared with dispersions in which the interaction did not occur.

References

Apr 1, 1977·Journal of Pharmaceutical Sciences·L V AllenD D Maness
Nov 1, 1973·Journal of Pharmaceutical Sciences·E I Stupak, T R Bates
Mar 1, 1972·Journal of Pharmaceutical Sciences·E I Stupak, T R Bates
Dec 1, 1969·Journal of Pharmaceutical Sciences·W L Chiou, S Riegelman

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Citations

Jan 17, 2004·International Journal of Pharmaceutics·Mayumi AsadaKazumi Danjo
Nov 16, 2002·International Journal of Pharmaceutics·Masataka SaitoTakashi Sonobe
Aug 6, 1999·Drug Development and Industrial Pharmacy·M M de VilliersJ J Gerber
Dec 29, 2020·Pharmaceutical Development and Technology·Mohamed Ahmed Naseef SolimanSamia Abd El-Kader Nour

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