Distal pancreas-coeliac axis resection with preoperative selective embolization of the coeliac axis: a single high-volume centre experience.

Langenbeck's Archives of Surgery
J H StorkholmC P Hansen

Abstract

Patients with ductal adenocarcinoma in the body and/or tail of the pancreas with involvement of the common hepatic artery and/or celiac axis have until recently been considered unresectable. In selected cases, distal pancreatectomy (DP) with en bloc celiac axis resection (DP-CAR) may be an option to achieve R0 resection. Patients with tumours in the body and/or tail of the pancreas locally advanced with involvement of the common hepatic artery and/or celiac axis, with no distant metastases, were evaluated for DP-CAR procedures. Preoperative embolization was performed 10-14 days prior to surgery to enhance collateral arterial supply for the liver and stomach. A total of 21 patients went through DP-CAR of whom 15 were preoperatively embolized. R0 resection vas achieved in 76% of the patients comparable to our standard distal pancreatectomies. The DP-CAR patients had a significant longer postoperative hospital stay, but no difference in major complications, including pancreatic fistulas compared with our standard distal pancreatectomies. No 30 nor 90 days postoperative mortality were recorded. Median survival in patients who underwent DP and DP-CAR procedures was 24.0 and 23.5 months, respectively (P > 0.5). Outcomes after DP-CAR ...Continue Reading

References

Sep 1, 1993·The British Journal of Surgery·C D JohnsonM Trede
Feb 1, 1996·The New England Journal of Medicine·R J BarstUNKNOWN Primary Pulmonary Hypertension Study Group
May 1, 1996·Annals of Surgery·M F BrennanD Klimstra
Jul 1, 1997·Journal of Surgical Oncology·T TakahashiH Katoh
May 11, 1999·Annals of Surgery·K D LillemoeC J Yeo
May 7, 2002·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Aaron R SassonBurton L Eisenberg
Aug 28, 2003·Langenbeck's Archives of Surgery·Satoshi KondoToshiaki Morikawa
Dec 3, 2003·The New England Journal of Medicine·John D BirkmeyerF Lee Lucas
Dec 17, 2003·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Margo ShoupMurray F Brennan
Dec 25, 2010·World Journal of Gastroenterology : WJG·Christian EipelBrigitte Vollmar
Jun 3, 2011·The New England Journal of Medicine·Jonathan F FinksJohn D Birkmeyer
May 10, 2012·The British Journal of Surgery·P SanjayJ A Windsor
Apr 5, 2013·World Journal of Gastrointestinal Surgery·Vyacheslav I EgorovEkaterina M Filippova
May 27, 2014·Surgery·Maximilian BockhornUNKNOWN International Study Group of Pancreatic Surgery
Apr 10, 2015·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Takuji YamagamiKazuo Awai
Apr 5, 2016·Journal of Clinical Anesthesia·Hidemasa TakahashiTakeo Suzuki
Aug 11, 2016·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Lee M OcuinAmer H Zureikat
Jan 4, 2017·Surgery·Claudio BassiUNKNOWN International Study Group on Pancreatic Surgery (ISGPS)
Mar 14, 2018·Annals of Surgical Oncology·Sjors KlompmakerUNKNOWN E-AHPBA DP-CAR study group

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Citations

Feb 3, 2021·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Yoshiaki MurakamiHiroyuki Otsuka

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