Distal Pancreatectomy Combined with Multivisceral Resection Is Associated with Postoperative Complication Rates and Survival Comparable to Those After Standard Procedures

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
Thomas MalinkaMarcus Bahra

Abstract

For pancreatic tumors located in the body or tail of the pancreas, distal pancreatectomy (DP) remains the surgical procedure of choice to achieve radical tumor removal. Purpose of this study was to evaluate outcome and overall survival of patients who underwent DP combined with multivisceral resection (MVR). Retrospective single-center case-matched analysis. Between January 1994 and June 2014, 494 consecutive patients were entered into a prospective database, and 126 patients undergoing DP + MVR (cases) were matched with 126 patients undergoing DP (controls) for gender, age, and underlying final diagnosis. There were no significant differences in patient demographics. Rates of postoperative pancreatic fistula (POPF) (36 (28.6%) vs. 29 (23.0%); p = 0.388) and postpancreatectomy hemorrhage (PPH) (7 (5.5%) vs. 5 (3.9%); p = 0.769) did not reveal any significant differences. Although operative time (237.8 ± 57.9 vs. 203.5 ± 34.5; p < 0.001) and the necessity for intraoperative transfusions (18 (14.3%) vs. 5 (4.0%); p < 0.001) was significantly higher, the number of patients with major complications (the Clavien-Dindo ≥ 3) was not increased (27 (19.8%) vs. 20 (15.9%); p = 0.332) in the DP + MVR group. Midterm survival analysis indic...Continue Reading

Associated Clinical Trials

Mar 23, 2020·Gerardo Blanco-Fernández

References

May 11, 1999·Annals of Surgery·K D LillemoeC J Yeo
Apr 12, 2002·American Journal of Surgery·Bridget N FahyRichard J Bold
Jul 9, 2005·Surgery·Claudio BassiUNKNOWN International Study Group on Pancreatic Fistula Definition
Sep 30, 2005·Annals of Surgery·Yuman FongMurray F Brennan
Jun 24, 2006·Annals of Surgery·John L CameronKenneth A Belcher
Apr 7, 2007·Annals of Surgery·Jörg KleeffMarkus W Büchler
Aug 2, 2007·Annals of Surgery·James T McPheeJennifer F Tseng
Aug 5, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Jennifer L IraniThomas E Clancy
Oct 12, 2010·Cardiovascular and Interventional Radiology·Timm DeneckeMatthias Glanemann
Jun 3, 2011·The New England Journal of Medicine·Jonathan F FinksJohn D Birkmeyer
Mar 1, 2012·North American Journal of Medical Sciences·Ake Andrén-Sandberg
Dec 26, 2013·Annals of Surgery·Bradley N ReamesJustin B Dimick
May 27, 2014·Surgery·Maximilian BockhornUNKNOWN International Study Group of Pancreatic Surgery
Dec 24, 2014·The British Journal of Surgery·F PayeUNKNOWN French Surgical Association (AFC)
Jan 9, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Birte KulemannHartwig Riediger
Oct 29, 2015·Annals of Surgical Oncology·Thijs de RooijUNKNOWN Dutch Pancreatic Cancer Group
Oct 28, 2016·Langenbeck's Archives of Surgery·Francesca PanzeriGiovanni Butturini
Feb 15, 2017·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·Fritz KleinMarcus Bahra

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Citations

Oct 27, 2018·HPB Surgery : a World Journal of Hepatic, Pancreatic and Biliary Surgery·T MalinkaM Bahra
Aug 21, 2020·World Journal of Surgical Oncology·Oliver BeetzGerrit Grannas
Dec 22, 2020·Cirugía española·Juan Manuel Castillo TuñónGerardo Blanco Fernández
May 1, 2021·Cancers·Kongyuan Wei, Thilo Hackert
Nov 9, 2021·Future Oncology·Monish Karunakaran, Savio George Barreto

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