Distinct association between the antagonistic jaw muscle activity levels and cardiac activity during chewing and NREM sleep in the freely moving guinea pigs

Neuroscience Letters
T KatoA Yoshida

Abstract

The aim of this study was to investigate the changes of the association between cardiac activity and the electromyographic (EMG) level of the antagonistic jaw muscles during chewing and NREM sleep in guinea pigs after systemic clonidine injections. Ten animals were prepared for chronic experiments to monitor sleep, cardiac activity and EMG activity of jaw-closing masseter (MAS) and jaw-opening anterior belly of digastric (ADG) muscles. The recordings were made for ten hours with the injections of saline or clonidine (10 μg/kg, i.p.). Integrated EMG activity of the two muscles and mean heart rate (mHR) were calculated for every 10-s epoch. During the two hours after clonidine injection, the duration of REM sleep and mHR were significantly reduced. During chewing, the high EMG activity level of the two muscles and the activity ratio between the two muscles were not modified although mHR was decreased. During NREM sleep, after clonidine injection, the low EMG activity level at baseline was further decreased by 20-30% in parallel to a decrease of mHR although the heterogeneity of the activity ratio remained unaltered. The results suggest that the maintenance of the activity level for the antagonistic jaw muscles are regulated by th...Continue Reading

References

Dec 16, 1977·European Journal of Clinical Pharmacology·A AutretH Schmitt
Sep 1, 1990·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·F FornaiM del Tacca
Oct 1, 1996·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·K MiyamotoK Tanne
Mar 26, 2003·Journal of Dental Research·T KatoG J Lavigne
Mar 28, 2003·The Journal of Pharmacology and Experimental Therapeutics·Mahmoud M El-Mas, Abdel A Abdel-Rahman
Sep 2, 2004·Journal of Sleep Research·T KatoG J Lavigne
Jul 25, 2009·European Journal of Oral Sciences·Yoko HasegawaYoshinobu Maeda
Oct 23, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Takafumi KatoToshifumi Morimoto
Jan 22, 2013·Autonomic Neuroscience : Basic & Clinical·Kenju Miki, Misa Yoshimoto
Apr 23, 2013·Journal of Prosthodontic Research·Takafumi KatoGilles J Lavigne
Oct 8, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Alessandro Silvani, Roger A L Dampney

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Citations

Jul 28, 2016·Neuroscience Research·Yasuha IkawaTomio Inoue

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