Distinct connectivity profiles predict different in-time processes of motor skill learning.

NeuroImage
Antonello BaldassarreGiorgia Committeri

Abstract

Learning through intensive practice has been largely observed in motor, sensory and higher-order cognitive processing. Neuroimaging studies have shown that learning phases are associated with different patterns of functional and structural neural plasticity in spatially distributed brain systems. Yet, it is unknown whether distinct neural signatures before practice can foster different subsequent learning stages over time. Here, we employed a bimanual implicit sequence reaction time task (SRTT) to investigate whether the rates of early (one day after practice) and late (one month after practice) post-training motor skill learning were predicted by distinct patterns of pre-training resting state functional connectivity (rs-FC), recorded with functional MRI. We observed that both motor learning descriptors were positively correlated with the strength of rs-FC among pairs of regions within a SRTT-relevant network comprising cerebellar as well as cortical and subcortical motor areas. Crucially, we detected a double dissociation such that early post-training learning was significantly associated with the functional connections within cerebellar regions, whereas late post-training learning was significantly related to the functional ...Continue Reading

References

Jan 1, 1989·Experimental Brain Research·A G CanavanR E Passingham
Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
Sep 1, 1995·NeuroImage·K J Worsley, K J Friston
Sep 8, 2001·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J MazziottaB Mazoyer
Sep 25, 2001·Neuron·C D GilbertR E Crist
May 8, 2002·Nature Reviews. Neuroscience·Maurizio Corbetta, Gordon L Shulman
May 17, 2002·Current Opinion in Neurobiology·Okihide HikosakaHiroyuki Nakahara
Nov 22, 2002·Experimental Brain Research·O HikosakaY Shimo
Apr 16, 2005·Current Opinion in Neurobiology·Julien Doyon, Habib Benali
Mar 15, 2006·NeuroImage·Khaled RestomThomas T Liu
Oct 6, 2006·Experimental Brain Research·Daniel A Cohen, Edwin M Robertson
Mar 21, 2007·NeuroImage·Randy L Buckner, Justin L Vincent
May 18, 2007·Journal of Neurophysiology·Ya-Weng TsengAmy J Bastian
Jun 20, 2007·Proceedings of the National Academy of Sciences of the United States of America·Nico U F DosenbachSteven E Petersen
Aug 21, 2007·Nature Reviews. Neuroscience·Michael D Fox, Marcus E Raichle
Sep 21, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Edwin M Robertson
Feb 6, 2008·Experimental Brain Research·Reza Shadmehr, John W Krakauer
Apr 11, 2008·Cerebral Cortex·A Di MartinoM P Milham
Sep 4, 2008·Journal of Experimental Psychology. Learning, Memory, and Cognition·James H HowardAndrew J Kelly
Oct 7, 2008·NeuroImage·Catherine J Stoodley, Jeremy D Schmahmann
May 12, 2009·Current Biology : CB·Neil B AlbertR Chris Miall
Oct 7, 2009·Proceedings of the National Academy of Sciences of the United States of America·Christopher M LewisMaurizio Corbetta
Jan 5, 2011·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Gustavo Deco, Maurizio Corbetta
Jun 10, 2011·Journal of Neurophysiology·B T Thomas YeoRandy L Buckner
Jun 15, 2011·NeuroImage·Andrea BrovelliDriss Boussaoud
Jul 19, 2011·Current Opinion in Neurobiology·John W Krakauer, Pietro Mazzoni
Jul 29, 2011·Journal of Neurophysiology·Randy L BucknerB T Thomas Yeo
Oct 19, 2011·Behavioural Brain Research·Virginia B Penhune, Christopher J Steele
Nov 15, 2011·Neuron·Eran Dayan, Leonardo G Cohen
Nov 15, 2011·Neuron·Lior Shmuelof, John W Krakauer
Nov 22, 2011·Neuron·Jonathan D PowerSteven E Petersen
Feb 9, 2012·Proceedings of the National Academy of Sciences of the United States of America·Antonello BaldassarreMaurizio Corbetta
May 31, 2012·Brain Connectivity·Susan Whitfield-Gabrieli, Alfonso Nieto-Castanon
Oct 3, 2012·PloS One·Sabrina TrappPatrick Ragert
Dec 1, 2012·NeuroImage·Robert M HardwickSimon B Eickhoff

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.