Distinct effects of perceptual quality on auditory word recognition, memory formation and recall in a neural model of sequential memory.

Frontiers in Systems Neuroscience
Paul Miller, Arthur Wingfield

Abstract

Adults with sensory impairment, such as reduced hearing acuity, have impaired ability to recall identifiable words, even when their memory is otherwise normal. We hypothesize that poorer stimulus quality causes weaker activity in neurons responsive to the stimulus and more time to elapse between stimulus onset and identification. The weaker activity and increased delay to stimulus identification reduce the necessary strengthening of connections between neurons active before stimulus presentation and neurons active at the time of stimulus identification. We test our hypothesis through a biologically motivated computational model, which performs item recognition, memory formation and memory retrieval. In our simulations, spiking neurons are distributed into pools representing either items or context, in two separate, but connected winner-takes-all (WTA) networks. We include associative, Hebbian learning, by comparing multiple forms of spike-timing-dependent plasticity (STDP), which strengthen synapses between coactive neurons during stimulus identification. Synaptic strengthening by STDP can be sufficient to reactivate neurons during recall if their activity during a prior stimulus rose strongly and rapidly. We find that a single...Continue Reading

Citations

Feb 13, 2013·Memory & Cognition·Nicole M AmichettiArthur Wingfield
May 20, 2014·Memory & Cognition·Katheryn A Q CousinsPaul Miller
Feb 2, 2016·The Journal of the Acoustical Society of America·Valeriy ShafiroRobert Risley
Nov 25, 2011·Human Brain Mapping·Cathérine C S DelnoozIvan Toni
Jul 1, 2015·Frontiers in Psychology·Arthur WingfieldAmanda Lash
Jun 20, 2016·Current Opinion in Neurobiology·Paul Miller
Jul 25, 2013·Journal of Speech, Language, and Hearing Research : JSLHR·Huiwen GoyM Kathleen Pichora-Fuller
Feb 17, 2018·Journal of Speech, Language, and Hearing Research : JSLHR·Margaret A KoeritzerJonathan E Peelle
May 14, 2016·Scientific Reports·Xingchao WangPinan Liu
May 28, 2019·Journal of Computational Neuroscience·Benjamin BallintynPaul Miller
Apr 17, 2020·PloS One·Elif Köksal ErsözFrédéric Lavigne
Jan 26, 2017·Frontiers in Aging Neuroscience·Nicole D AyasseArthur Wingfield

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