Distinct functional networks within the cerebellum and their relation to cortical systems assessed with independent component analysis.

NeuroImage
Vitaly I DobromyslinRegina E McGlinchey

Abstract

Cerebellar functional circuitry has been examined in several prior studies using resting fMRI data and seed-based procedures, as well as whole-brain independent component analysis (ICA). Here, we hypothesized that ICA applied to functional data from the cerebellum exclusively would provide increased sensitivity for detecting cerebellar networks compared to previous approaches. Consistency of group-level networks was assessed in two age- and sex-matched groups of twenty-five subjects each. Cerebellum-only ICA was compared to the traditional whole-brain ICA procedure to examine the potential gain in sensitivity of the novel method. In addition to replicating a number of previously identified cerebellar networks, the current approach revealed at least one network component that was not apparent with the application of whole brain ICA. These results demonstrate the gain in sensitivity attained through specifying the cerebellum as a target structure with regard to the identification of robust and reliable networks. The use of similar procedures could be important in further expanding on previously defined patterns of cerebellar functional anatomy, as well as provide information about unique networks that have not been explored in pr...Continue Reading

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Citations

Sep 3, 2013·The Cerebellum·Leonard F KoziolTadashi Yamazaki
Jan 18, 2016·NeuroImage·Matthew P SchroederLei Wang
Oct 21, 2014·Journal of Magnetic Resonance Imaging : JMRI·Xiaojuan GuoLi Yao
Nov 20, 2014·Alcoholism, Clinical and Experimental Research·Catherine B FortierRegina E McGlinchey
May 23, 2015·NeuroImage·Michael C RiedelAngela R Laird
Apr 9, 2015·Frontiers in Human Neuroscience·Ann K ShinnBruce M Cohen
May 21, 2016·Frontiers in Neuroscience·Changqing WangAnqi Qiu
May 12, 2016·Human Brain Mapping·Tawfik Moher AlsadyFlorian Beissner
Feb 15, 2019·Brain Imaging and Behavior·Antonio GiorgioSilvia Benemei
Feb 26, 2019·Human Brain Mapping·Qingyu ZhaoKilian M Pohl
Apr 14, 2016·Cerebral Cortex·Kajsa M IgelströmMichael S A Graziano
Sep 2, 2017·Frontiers in Aging Neuroscience·Ke LiuXiaojuan Guo

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