Distinct phytochrome actions in nonvascular plants revealed by targeted inactivation of phytobilin biosynthesis.

Proceedings of the National Academy of Sciences of the United States of America
Yu-Rong ChenShih-Long Tu

Abstract

The red/far-red light photoreceptor phytochrome mediates photomorphological responses in plants. For light sensing and signaling, phytochromes need to associate with open-chain tetrapyrrole molecules as the chromophore. Biosynthesis of tetrapyrrole chromophores requires members of ferredoxin-dependent bilin reductases (FDBRs). It was shown that LONG HYPOCOTYL 2 (HY2) is the only FDBR in flowering plants producing the phytochromobilin (PΦB) for phytochromes. However, in the moss Physcomitrella patens, we found a second FDBR that catalyzes the formation of phycourobilin (PUB), a tetrapyrrole pigment usually found as the protein-bound form in cyanobacteria and red algae. Thus, we named the enzyme PUB synthase (PUBS). Severe photomorphogenic phenotypes, including the defect of phytochrome-mediated phototropism, were observed in Physcomitrella patens when both HY2 and PUBS were disrupted by gene targeting. This indicates HY2 and PUBS function redundantly in phytochrome-mediated responses of nonvascular plants. Our studies also show that functional PUBS orthologs are found in selected lycopod and chlorophyte genomes. Using mRNA sequencing for transcriptome profiling, we demonstrate that expression of the majority of red-light-respons...Continue Reading

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Citations

Feb 9, 2013·Plant Physiology·Nan-Lan HuangAnthony H C Huang
Jun 28, 2014·Nature Communications·Florian MaumusGuillaume Blanc
Oct 1, 2014·Proceedings of the National Academy of Sciences of the United States of America·Deqiang DuanmuAlexandra Z Worden
Apr 8, 2015·Plant Signaling & Behavior·Liang BaoTomomichi Fujita
Jan 29, 2014·Plant Science : an International Journal of Experimental Plant Biology·Anja PossartAndreas Hiltbrunner
Jan 25, 2013·Proceedings of the National Academy of Sciences of the United States of America·Deqiang DuanmuJ Clark Lagarias
Jan 1, 2014·Frontiers in Ecology and Evolution·Nathan C RockwellDebashish Bhattacharya
Mar 6, 2015·PloS One·Rigoberto Medina-AndrésVerónica Lira-Ruan
Mar 8, 2016·Environmental Microbiology·Benjamin LedermannNicole Frankenberg-Dinkel
Jan 21, 2017·The New Phytologist·Nathan C RockwellJohn Clark Lagarias
Mar 1, 2017·Plant, Cell & Environment·Deqiang DuanmuJ Clark Lagarias
May 14, 2017·Photochemistry and Photobiology·Carlos E HernandoJulieta L Mateos
Apr 24, 2018·The Plant Journal : for Cell and Molecular Biology·Pierre-François PerroudStefan A Rensing
Apr 4, 2020·The Journal of Biological Chemistry·Donald A BryantMartin J Warren
Aug 7, 2014·The Journal of Biological Chemistry·Kristina E OverkampNicole Frankenberg-Dinkel
Nov 28, 2020·Planta·Durga Prasad Biswal, Kishore Chandra Sekhar Panigrahi
Apr 8, 2019·Current Opinion in Structural Biology·Masakazu SugishimaKeiichi Fukuyama
May 29, 2018·Plant Science : an International Journal of Experimental Plant Biology·Giuseppina ReaAutar K Mattoo
Apr 30, 2014·Plant Physiology·Chiung-Yun ChangShih-Long Tu

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