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Distinct structural transitions of chromatin topological domains coordinate hormone-induced gene regulation

bioRxiv

Mar 13, 2014

François Le DilyMiguel Beato

Abstract

The human genome is segmented into Topologically Associating Domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we described the distribution of Progestin-induced chromatin modifications and changes in transcription...read more

Mentioned in this Paper

Hormones
Expanding
Regulon
DNA Topology Regulation
Breast Cancer Cell
Study of Epigenetics
Physiological Aspects
Progestins
Transcription, Genetic
Proximal Muscle
6
6
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Distinct structural transitions of chromatin topological domains coordinate hormone-induced gene regulation

bioRxiv

Mar 13, 2014

François Le DilyMiguel Beato

PMID: 990003293

DOI: 10.1101/003293

Abstract

The human genome is segmented into Topologically Associating Domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we described the distribution of Progestin-induced chromatin modifications and changes in transcription...read more

Mentioned in this Paper

Hormones
Expanding
Regulon
DNA Topology Regulation
Breast Cancer Cell
Study of Epigenetics
Physiological Aspects
Progestins
Transcription, Genetic
Proximal Muscle
6
6

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