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Distinct structural transitions of chromatin topological domains coordinate hormone-induced gene regulation

bioRxiv

Mar 13, 2014

François Le DilyMiguel Beato

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Abstract

The human genome is segmented into Topologically Associating Domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we described the distribution of Progestin-induced chromatin modifications and changes in transcription...read more

Mentioned in this Paper

Gene Expression
Study of Epigenetics
Cellular Component Organization
Progestin [EPC]
Breast Cancer Cell
Chromatin
Three-dimensional
Chromatin Immunoprecipitation
Genome
Physiological Aspects
6
6
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  • Distinct structural transitions of chromatin topological domains coordinate hormone-induced gene regulation

    bioRxiv

    Mar 13, 2014

    François Le DilyMiguel Beato

    PMID: 990003293

    DOI: 10.1101/003293

    Abstract

    The human genome is segmented into Topologically Associating Domains (TADs), but the role of this conserved organization during transient changes in gene expression is not known. Here we described the distribution of Progestin-induced chromatin modifications and changes in transcription...read more

    Mentioned in this Paper

    Gene Expression
    Study of Epigenetics
    Cellular Component Organization
    Progestin [EPC]
    Breast Cancer Cell
    6
    6

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