PMID: 9558302May 19, 1998Paper

Distinctive dermatoscopic features of acral lentiginous melanoma in situ from plantar melanocytic nevi and their histopathologic correlation

Journal of Cutaneous Medicine and Surgery
Y Kawabata, K Tamaki

Abstract

An acral lentiginous melanoma in situ on the sole is often difficult to differentiate with the naked eye from an acquired plantar melanocytic nevus. Recent technical advances in epiluminescence microscopy have contributed to the differentiation of these two pigmented skin lesions. In this study, the correlation between dermatoscopic and histopathologic findings of acral lentiginous melanoma in situ on the sole are compared to those of acquired plantar melanocytic nevi. Three acral lentiginous melanomas in situ on the sole, and two cases of acral lentiginous melanoma were compared with 50 acquired plantar melanocytic nevi by means of dermatoscopy and histopathology. The dermatoscopic surface profiles of acquired melanocytic nevi were composed of linear pigmentation accentuated mainly on the sulcus superficialis. Histologically, some areas of the sulcus superficialis corresponded to rete ridges of the epidermis, and nests of nevus cells were also often located there. In contrast, the acral lentiginous melanomas in situ showed diffuse, irregularly shaped pigmentation distributed in a disorderly fashion over the entire surface. Histologically, isolated areas of proliferation and small nest formations of atypical melanocytes were ir...Continue Reading

References

Oct 1, 1987·Journal of the American Academy of Dermatology·H PehambergerK Wolff
Jan 1, 1982·Hospital Practice·T B Fitzpatrick
Apr 1, 1980·The Journal of Dermatology·M HosokawaR Abe
Feb 1, 1996·The American Journal of Dermatopathology·R AkasuK Tamaki

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Citations

May 1, 2017·Melanoma Management·Maressa C Criscito, Jennifer A Stein
Dec 7, 2018·The Cochrane Database of Systematic Reviews·Jacqueline DinnesUNKNOWN Cochrane Skin Cancer Diagnostic Test Accuracy Group
Dec 7, 2018·The Cochrane Database of Systematic Reviews·Jacqueline DinnesUNKNOWN Cochrane Skin Cancer Diagnostic Test Accuracy Group
May 27, 2005·Pediatric Dermatology·Iris ZalaudekGiuseppe Argenziano
Sep 10, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Iris ZalaudekRalph P Braun
Feb 27, 2003·The American Journal of Surgical Pathology·Gerardo FerraraH Peter Soyer
Nov 6, 2004·The Australasian Journal of Dermatology·Andreas Blum, Rainer Hofmann-Wellenhof

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