Distinctive Microbiome Type Distribution in a Young Adult Balinese Cohort May Reflect Environmental Changes Associated with Modernization.

Microbial Ecology
Clarissa Asha FebiniaAndrew J. Holmes

Abstract

An important public health question is understanding how changes in human environments can drive changes in the gut microbiota that influence risks associated with human health and wellbeing. It is well-documented that the modernization of societies is strongly correlated with intergenerational change in the frequency of nutrition-related chronic diseases in which microbial dysbiosis is implicated. The population of Bali, Indonesia, is well-positioned to study the interconnection between a changing food environment and microbiome patterns in its early stages, because of a recent history of modernization. Here, we characterize the fecal microbiota and diet history of the young adult women in Bali, Indonesia (n = 41) in order to compare microbial patterns in this generation with those of other populations with different histories of a modern food environment (industrialized supply chain). We found strong support for two distinct fecal microbiota community types in our study cohort at similar frequency: a Prevotella-rich (Type-P) and a Bacteroides-rich (Type-B) community (p < 0.001, analysis of similarity, Wilcoxon test). Although Type-P individuals had lower alpha diversity (p < 0.001, Shannon) and higher incidence of obesity, mu...Continue Reading

References

Aug 15, 2003·Advances in Experimental Medicine and Biology·Sangkot MarzukiPatcharin Pramoonjago
Dec 2, 2008·Nature·Peter J TurnbaughJeffrey I Gordon
Aug 4, 2010·Proceedings of the National Academy of Sciences of the United States of America·Carlotta De FilippoPaolo Lionetti
Apr 22, 2011·Nature·Manimozhiyan ArumugamPeer Bork
Sep 3, 2011·Science·Gary D WuJames D Lewis
Jun 16, 2012·Nature·UNKNOWN Human Microbiome Project Consortium
Jun 16, 2012·Nature·Tanya YatsunenkoJeffrey I Gordon
Nov 30, 2012·Nucleic Acids Research·Christian QuastFrank Oliver Glöckner
Jan 5, 2013·Environmental Microbiology·Mirjana Rajilić-StojanovićWillem M de Vos
Aug 30, 2013·Nature·Emmanuelle Le ChatelierOluf Pedersen
Dec 18, 2013·Nature·Lawrence A DavidPeter J Turnbaugh
Apr 17, 2014·Nature Communications·Stephanie L SchnorrAlyssa N Crittenden
Jun 10, 2014·Proceedings of the National Academy of Sciences of the United States of America·Jun WangJohn F Baines
Oct 10, 2014·Cell Host & Microbe·Dan KnightsRob Knight
Mar 26, 2015·Nature Communications·Alexandra J Obregon-TitoCecil M Lewis
Dec 15, 2015·Nucleic Acids Research·Andreas WilkeFolker Meyer
Jan 15, 2016·Nature·Erica D SonnenburgJustin L Sonnenburg
Apr 14, 2016·Microbiome·Anastassia GorvitovskaiaSusan M Huse
May 24, 2016·Nature Methods·Benjamin J CallahanSusan P Holmes
Oct 27, 2016·PeerJ·Torbjørn RognesFrédéric Mahé
Feb 16, 2017·Environmental Microbiology·Leonardo MancabelliMarco Ventura
Mar 11, 2017·Frontiers in Cellular and Infection Microbiology·Ana C F de MoraesSandra R G Ferreira
Dec 20, 2017·Nature Microbiology·Paul I CosteaPeer Bork
Oct 10, 2018·Methods in Molecular Biology·Michael Hall, Robert G Beiko
Nov 6, 2018·Cell·Pajau VangayDan Knights
Nov 16, 2018·PLoS Biology·Aashish R JhaJustin L Sonnenburg
Jul 26, 2019·Nature Biotechnology·Evan BolyenJ Gregory Caporaso

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriotherapy

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.

Bacteriotherapy (ASM)

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.