Distinguishing benign notochordal cell tumors from vertebral chordoma

Skeletal Radiology
Takehiko YamaguchiKatsuro Tomita

Abstract

The objective was to characterize imaging findings of benign notochordal cell tumors (BNCTs). Clinical and imaging data for 9 benign notochordal cell tumors in 7 patients were reviewed retrospectively. Conventional radiographs (n = 9), bone scintigrams (n = 2), computed tomographic images (n = 7), and magnetic resonance images (n = 8) were reviewed. Eight of the 9 lesions were stained with hematoxylin-eosin and microscopically examined. There were 3 male and 4 female patients with an age range of 22 to 55 years (average age, 44 years). Two patients had two lesions at different sites. The lesions involved the cervical spine in 4 patients, the lumbar spine in 2, the sacrum in 2, and the coccyx in 1. The most common symptom was mild pain. The lesions of 2 patients were found incidentally during imaging studies for unrelated conditions. Five patients underwent surgical procedures. One patient died of surgical complications. All other patients have been well without recurrent or progressive disease for 13 to 84 months. Radiographs usually did not reveal significant abnormality. Five lesions exhibited subtle sclerosis and 1 showed intense sclerosis. Technetium bone scan did not reveal any abnormal uptake. Computed tomography images h...Continue Reading

References

Aug 18, 1999·Skeletal Radiology·A J DarbyD C Jaffray
Feb 27, 2003·The American Journal of Surgical Pathology·Michael KyriakosLawrence G Lenke
Aug 19, 2003·Spine·Hideki MurakamiKatsuro Tomita
Apr 2, 2005·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Takehiko YamaguchiYoshihiko Ueda
Dec 6, 2005·Histopathology·A ChauvelJ-M Coindre
Sep 27, 2007·The American Journal of Surgical Pathology·Vikram DeshpandeAndrew E Rosenberg

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Citations

Nov 27, 2008·Clinical Nuclear Medicine·Soon-Ah Park, Hun Soo Kim
Feb 24, 2011·AJR. American Journal of Roentgenology·Tomokazu NishiguchiYukio Miki
May 11, 2012·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Justin M M Cates, Cheryl M Coffin
May 27, 2014·Neuro-Chirurgie·B GeorgeK Beccaria
Mar 19, 2009·Acta neurochirurgica·Jeroen R CoppensWilliam T Couldwell
May 17, 2011·Neurologia i neurochirurgia polska·Dariusz AdamekKrystyna Gałązka
Oct 31, 2015·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Sum LeongWilliam Torreggiani
Sep 12, 2013·The Spine Journal : Official Journal of the North American Spine Society·Mehala TharmabalaRani Kanthan
Jun 17, 2011·Seminars in Diagnostic Pathology·Roberto A GarciaKrishnan K Unni
Sep 29, 2009·Journal of Neuroradiology. Journal De Neuroradiologie·A A K Abdel Razek, M Castillo
Jul 29, 2009·Orthopedics·Anthony D UglialoroJoseph Benevenia
Jan 17, 2014·Histopathology·Florian PulsD Chas Mangham
Aug 12, 2015·PM & R : the Journal of Injury, Function, and Rehabilitation·Christopher PlastarasBryan Pukenas
Mar 16, 2013·Diagnostic and Interventional Imaging·P SouteyrandC Chagnaud
Jan 23, 2015·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Jennifer KreshakDaniel Vanel
Dec 24, 2014·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Zubad A NewazMadhu K Nair
Dec 3, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Feifei PuZengwu Shao
Oct 26, 2018·Journal of Clinical Pathology·Jiang DuGuilin Li
Apr 17, 2013·The American Journal of Surgical Pathology·Scott R LauerSharon W Weiss
Aug 5, 2017·Skeletal Radiology·Abdulrehman ArainTimothy A Damron
Feb 27, 2020·Der Pathologe·Susanne ScheiplBernadette Liegl
Nov 8, 2016·The American Journal of Surgical Pathology·Jodi M CarterCarrie Y Inwards
Aug 23, 2020·Pathology International·Masayuki Shintaku, Ryutaro Kikuchi
May 1, 2012·The Neuroradiology Journal·R ConfortiG Paolisso
Jan 30, 2018·Clinical Case Reports·Satoshi TatedaHiroshi Ozawa
Jan 9, 2017·Skeletal Radiology·Connie ChangMiriam Bredella
Apr 10, 2018·Current Radiology Reports·Rene G C SantegoedsChristianne M Hoeberigs
Nov 3, 2009·The Journal of the American Academy of Orthopaedic Surgeons·Daniel M SciubbaZiya L Gokaslan
Apr 6, 2019·Journal of Korean Medical Science·Yoon Jin Cha, Yeon Lim Suh
Mar 9, 2011·Journal of Neuro-oncology·Roberto Jose Diaz, Michael D Cusimano
Mar 20, 2019·Clinical Neuroradiology·Shivaprakash B HiremathMaria Isabel Vargas
Feb 17, 2021·The Spine Journal : Official Journal of the North American Spine Society·Zach PenningtonDaniel M Sciubba
Feb 2, 2021·Skeletal Radiology·Joshua T OlsonStephen M Broski
Feb 4, 2010·Archives of Pathology & Laboratory Medicine·Hoda Zeinab M Amer, Meera Hameed

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Methods Mentioned

BETA
biopsy
biopsies

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