Distraction osteogenesis and histogenesis in beagle dogs: the effect of gradual mandibular osteodistraction on bone and gingiva

Journal of Periodontology
J B CopeDavid E Muirhead

Abstract

No study has systematically evaluated the effect of distraction osteogenesis on the gingival tissues. Therefore, this study was designed to analyze the newly formed bone and gingiva during the consolidation period of mandibular osteodistraction using standard histologic techniques. Seventeen skeletally mature male beagle dogs underwent 10 mm of bilateral interdental mandibular lengthening. After distraction, the regenerates were allowed to consolidate for 0, 2, 4, 6, or 8 weeks, then the animals were sacrificed and tissues harvested for analysis. Mineralization began at the host bone margins at the end of the distraction period, followed by a progressive increase in bone surface area, with a concomitant decrease in fibrous tissue. The gingiva initially underwent mild inflammatory and reactive changes during distraction and during the first few weeks of consolidation. The rate of bone formation gradually increased from the end of distraction to the fourth week of consolidation, at which time it remained constant until sometime before the eighth week, when it tapered off slightly as remodeling began. From the second through the eighth week of consolidation, regenerative changes and neohistogenesis were seen in the gingival tissue...Continue Reading

References

Jan 1, 1992·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·J T Mellonig
Dec 1, 1992·Acta Orthopaedica Scandinavica·J I PeltonenK A Aalto
May 1, 1974·Journal of Periodontology·P J Boyne
Apr 1, 1973·Journal of Periodontology·W H Hiatt, R G Schallhorn
Dec 1, 1994·Acta Orthopaedica Scandinavica·B SchumacherI Hvid
Jun 1, 1993·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M S BlockM Matthews
Jan 1, 1996·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·R WindhagerH Plenk
Mar 1, 1997·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·J AronsonC K Lumpkin
Mar 20, 1998·International Journal of Oral and Maxillofacial Surgery·T OdaM Ueda
Oct 28, 1998·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·E J Liou, C S Huang
Dec 10, 1998·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·M R MakarovM L Samchukov
Apr 8, 1999·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·J B CopeA M Cherkashin
May 13, 1999·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·W H BellC A Guerrero
Jan 1, 1997·The Journal of Craniofacial Surgery·S U Stucki-McCormick
Jun 18, 1999·Seminars in Orthodontics·B H Grayson, P E Santiago
Jun 18, 1999·Seminars in Orthodontics·P R Hanson, M B Melugin
Jun 18, 1999·Seminars in Orthodontics·C A GuerreroA M Rodríguez
Aug 7, 1999·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·J B CopeP Franco
Sep 4, 1999·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·S W SmithJ B Cope
Jun 26, 2001·International Journal of Oral and Maxillofacial Surgery·J B Cope, M L Samchukov

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Citations

Dec 31, 2003·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Lim K Cheung, Qian Zhang
May 8, 2003·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·Richard A HopperJoseph G McCarthy
Jul 4, 2007·The Angle Orthodontist·Mehmet BayramAlper Alkan
Apr 22, 2015·Oral and Maxillofacial Surgery·Aydin GülsesYahya Açil
Oct 28, 2008·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Pedro E G Soares CorreiaMaurice Y Mommaerts
Oct 26, 2005·Journal of Dental Research·L C WangH Mitani
Apr 1, 2014·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Matthew D McBridePeter H Buschang
Aug 28, 2014·Journal of Biomechanical Engineering·Uriel ZapataLynne A Opperman
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Hussam S Batal, David A Cottrell
Nov 5, 2011·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Adam C SpencerPeter H Buschang

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