Distress improves after mindfulness training for progressive MS: A pilot randomised trial

Multiple Sclerosis : Clinical and Laboratory Research
A BogosianRona Moss-Morris

Abstract

Mindfulness-based interventions have been shown to effectively reduce anxiety, depression and pain in patients with chronic physical illnesses. We assessed the potential effectiveness and cost-effectiveness of a specially adapted Skype distant-delivered mindfulness intervention, designed to reduce distress for people affected by primary and secondary progressive MS. Forty participants were randomly assigned to the eight-week intervention (n = 19) or a waiting-list control group (n = 21). Participants completed standardised questionnaires to measure mood, impact of MS and symptom severity, quality of life and service costs at baseline, post-intervention and three-month follow-up. Distress scores were lower in the intervention group compared with the control group at post-intervention and follow-up (p < 0.05), effect size -0.67 post-intervention and -0.97 at follow-up. Mean scores for pain, fatigue, anxiety, depression and impact of MS were reduced for the mindfulness group compared with control group at post-therapy and follow-up; effect sizes ranged from -0.27 to -0.99 post-intervention and -0.29 to -1.12 at follow-up. There were no differences in quality-adjusted life years, but an 87.4% probability that the intervention saves...Continue Reading

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References

Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Sep 15, 1995·Statistics in Medicine·R H Browne
Nov 10, 2000·General Hospital Psychiatry·N Mills, J Allen
Mar 16, 2001·Trends in Neurosciences·J Deuchars, S Deuchars
May 4, 2001·Brain : a Journal of Neurology·J HobartA Thompson
Jan 5, 2002·The British Journal of Psychiatry : the Journal of Mental Science·Chris EvansKerry Audin
Jul 31, 2003·Journal of Paediatrics and Child Health·M S Gold, UNKNOWN Anaphylaxis Working Party, Australasian Society of Clinical Immunology and Allergy
Mar 23, 2004·BMJ : British Medical Journal·David C MohrDaniel Pelletier
Jul 17, 2004·Journal of Psychosomatic Research·Paul GrossmanHarald Walach
Dec 1, 2004·Statistics in Medicine·Ian R White, Simon G Thompson
Oct 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·J C HobartA J Thompson
Feb 3, 2006·Tropical Medicine & International Health : TM & IH·S N KibonaG W Lubega
Jul 4, 2006·CNS Spectrums·Jeffrey L CummingsDaniel Weintraub
Jul 11, 2007·Statistical Methods in Medical Research·James R CarpenterIan R White
Sep 17, 2008·PharmacoEconomics·Paul McCroneAlan Thompson
Jun 24, 2009·Behavioural and Cognitive Psychotherapy·Paul ChadwickDave Dagnan
May 27, 2011·Multiple Sclerosis : Clinical and Laboratory Research·Nadina B LincolnCeri Phillips
Jan 8, 2013·Mindfulness·Rebecca S CraneMelanie J V Fennell
Apr 27, 2013·Health and Quality of Life Outcomes·Ayse Kuspinar, Nancy E Mayo
Sep 21, 2013·Journal of Neurology, Neurosurgery, and Psychiatry·I S MackenzieJ O'Riordan
Jan 21, 2014·BMC Neurology·Robert SimpsonStewart Mercer
Jul 1, 2014·Brain and Cognition·Barbara TomasinoFranco Fabbro

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Citations

Sep 20, 2015·Neurología : publicación oficial de la Sociedad Española de Neurología·A Muñoz San JoséC Bayón Pérez
May 31, 2016·British Journal of Health Psychology·Angeliki BogosianRona Moss-Morris
Apr 30, 2015·Multiple Sclerosis : Clinical and Laboratory Research·Robert SimpsonStewart Mercer
Oct 13, 2016·Expert Review of Neurotherapeutics·Mariarosa RottoliValeria Barcella
Dec 28, 2017·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Alison BarryEric J Downer
Feb 28, 2018·Multiple Sclerosis : Clinical and Laboratory Research·Cesare CavaleraFrancesco Pagnini
Apr 11, 2018·Current Treatment Options in Neurology·Myriam VenasseLara A Pilutti
Jun 26, 2018·The Clinical Neuropsychologist·Siew-Tim LaiVenus Tang
Jul 10, 2018·Multiple Sclerosis : Clinical and Laboratory Research·Angela SendersLynne Shinto
Aug 24, 2018·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Martina ChirraAristide Merola
Sep 11, 2016·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Manabu MakinodanToshifumi Kishimoto
Mar 7, 2018·International Journal of MS Care·Angela SendersLynne Shinto
Jun 7, 2018·Frontiers in Behavioral Neuroscience·Barbara WillekensNathalie Cools
Jul 1, 2020·Pilot and Feasibility Studies·Fiona J R EcclesJane Simpson
Jul 20, 2017·Hand : Official Journal of the American Association for Hand Surgery·Reinier B BeksAna Maria Vranceanu
Jun 14, 2018·International Journal of MS Care·Cristiano CrescentiniFranco Fabbro
Jan 29, 2021·Journal of Geriatric Psychiatry and Neurology·Angeliki BogosianPatricia Cubi-Molla
Jan 22, 2021·Multiple Sclerosis and Related Disorders·Jennifer DunneLucinda J Black
Nov 7, 2020·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Pamela NewlandVerna Hendricks-Ferguson
Mar 16, 2021·Multiple Sclerosis : Clinical and Laboratory Research·Kathleen M ZackowskiAnthony Feinstein
Apr 21, 2021·Multiple Sclerosis : Clinical and Laboratory Research·Anthony M HarrisonSam Norton

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Methods Mentioned

BETA
Cognitive Therapy

Clinical Trials Mentioned

ISRCTN93263909

Software Mentioned

Skype

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