Distributed cerebellar plasticity implements generalized multiple-scale memory components in real-robot sensorimotor tasks

Frontiers in Computational Neuroscience
Claudia CasellatoAlessandra Pedrocchi

Abstract

The cerebellum plays a crucial role in motor learning and it acts as a predictive controller. Modeling it and embedding it into sensorimotor tasks allows us to create functional links between plasticity mechanisms, neural circuits and behavioral learning. Moreover, if applied to real-time control of a neurorobot, the cerebellar model has to deal with a real noisy and changing environment, thus showing its robustness and effectiveness in learning. A biologically inspired cerebellar model with distributed plasticity, both at cortical and nuclear sites, has been used. Two cerebellum-mediated paradigms have been designed: an associative Pavlovian task and a vestibulo-ocular reflex, with multiple sessions of acquisition and extinction and with different stimuli and perturbation patterns. The cerebellar controller succeeded to generate conditioned responses and finely tuned eye movement compensation, thus reproducing human-like behaviors. Through a productive plasticity transfer from cortical to nuclear sites, the distributed cerebellar controller showed in both tasks the capability to optimize learning on multiple time-scales, to store motor memory and to effectively adapt to dynamic ranges of stimuli.

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Citations

Mar 15, 2016·Frontiers in Neuroanatomy·Masato Gosui, Tadashi Yamazaki
Oct 7, 2015·IEEE Transactions on Bio-medical Engineering·Alberto AntoniettiAlessandra Pedrocchi
Jul 28, 2016·Frontiers in Cellular Neuroscience·Egidio D'AngeloEduardo Ros
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Mar 22, 2019·Frontiers in Cellular Neuroscience·Letizia MoscatoEgidio D'Angelo
Apr 23, 2020·Frontiers in Neuroinformatics·Hiroshi YamauraTadashi Yamazaki
Jul 14, 2017·Frontiers in Cellular Neuroscience·Daniela GandolfiEgidio D'Angelo
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Apr 9, 2020·International Journal of Molecular Sciences·Francesca PrestoriLisa Mapelli
Jan 23, 2021·Neuroscience·Tadashi YamazakiHiroshi Yamaura
Nov 6, 2020·Bioinspiration & Biomimetics·Hari Teja KalidindiEgidio Falotico
Apr 27, 2021·Frontiers in Cellular Neuroscience·Rin KuriyamaTadashi Yamazaki
Jun 18, 2021·Frontiers in Cellular Neuroscience·Petruţ A BogdanOliver Rhodes
Jul 7, 2021·PLoS Computational Biology·Simon P OrozcoReza Shadmehr

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