Distribution and amplification of interstitial telomeric sequences (ITSs) in Australian dragon lizards support frequent chromosome fusions in Iguania

PloS One
Kornsorn SrikulnathT Ezaz

Abstract

Telomeric sequences are generally located at the ends of chromosomes; however, they can also be found in non-terminal chromosomal regions when they are known as interstitial telomeric sequences (ITSs). Distribution of ITSs across closely related and divergent species elucidates karyotype evolution and speciation as ITSs provide evolutionary evidence for chromosome fusion. In this study, we performed physical mapping of telomeric repeats by fluorescence in situ hybridisation (FISH) in seven Australian dragon lizards thought to represent derived karyotypes of squamate reptiles and a gecko lizard with considerably different karyotypic feature. Telomeric repeats were present at both ends of all chromosomes in all species, while varying numbers of ITSs were also found on microchromosomes and in pericentromeric or centromeric regions on macrochromosomes in five lizard species examined. This suggests that chromosomal rearrangements from ancestral squamate reptiles to Iguania occurred mainly by fusion between ancestral types of acrocentric chromosomes and/or between microchromosomes, leading to appearance of bi-armed macrochromosomes, and in the reduction of microchromosome numbers. These results support the previously proposed hypothe...Continue Reading

References

Sep 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J MeyneR K Moyzis
Jul 27, 1999·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·W S Liu, K Fredga
Sep 20, 2005·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Yoichi MatsudaKiyokazu Agata
Dec 7, 2005·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Tariq EzazJennifer A Marshall Graves
Nov 18, 2006·Proceedings of the National Academy of Sciences of the United States of America·Kazumi MatsubaraYoichi Matsuda
Apr 21, 2007·Science·Alexander E QuinnJennifer A Marshall Graves
Jan 28, 2009·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Tariq EzazJennifer A Marshall Graves
Feb 4, 2009·Cytogenetic and Genome Research·A Ruiz-HerreraE Giulotto
Mar 20, 2010·Cytogenetic and Genome Research·D O'MeallyT Ezaz
Oct 1, 2008·Integrative and Comparative Biology·Ettore Olmo
Oct 12, 2011·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Vladimir A TrifonovMalcolm A Ferguson-Smith
May 1, 2013·BMC Evolutionary Biology·R Alexander PyronJohn J Wiens
May 25, 2013·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·M J YoungT Ezaz
Dec 18, 2013·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Kornsorn SrikulnathYoichi Matsuda
Jan 18, 2014·Evolution; International Journal of Organic Evolution·Michail RovatsosLukáš Kratochvíl
Aug 8, 2015·PloS One·Michail RovatsosMartina Johnson Pokorná
Sep 21, 2017·Mutation Research. Reviews in Mutation Research·Alejandro D Bolzán
Dec 13, 2017·Genes·Michail RovatsosLukáš Kratochvíl
Dec 29, 2017·Genes·Barbora AugstenováMichail Rovatsos

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Citations

May 3, 2020·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Worapong SingchatKornsorn Srikulnath
Jun 21, 2020·Genes·Lorenzo ClementeMichail Rovatsos
Nov 5, 2020·Cells·Worapong SingchatKornsorn Srikulnath

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Fluorescence Imaging

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