Distribution and characteristics of COPD phenotypes - results from the Polish sub-cohort of the POPE study

International Journal of Chronic Obstructive Pulmonary Disease
Aleksander KaniaAdam Barczyk

Abstract

This study aimed to examine the distribution of predefined phenotypes, demographic data, clinical outcomes, and treatment of patients who were included in the Polish cohort of the Phenotypes of COPD in Central and Eastern Europe (POPE) study. This was a sub-analysis of the data from the Polish cohort of the POPE study, an international, multicenter, observational cross-sectional survey of COPD patients in Central and Eastern European countries. The study included patients aged >40 years, with a confirmed diagnosis of COPD, and absence of exacerbation for at least 4 weeks before study inclusion. A total of seven Polish centers participated in the study. Among the 430 Polish COPD patients enrolled in the study, 61.6% were non-exacerbators (NON-AE), 25.3% were frequent exacerbators with chronic bronchitis (AE CB), 7.9% were frequent exacerbators without chronic bronchitis (AE NON-CB), and 5.1% met the definition of asthma-COPD overlap syndrome (ACOS). There were statistically significant differences among these phenotypes in terms of symptom load, lung function, comorbidities, and treatment. Patients with the AE CB phenotype were most symptomatic with worse lung function, and more frequently reported anxiety and depression. Patien...Continue Reading

Citations

Oct 30, 2020·Journal of Clinical Medicine·Joon Young Choi, Chin Kook Rhee
Mar 25, 2021·International Journal of Chronic Obstructive Pulmonary Disease·Zorica LazicVojislav Cupurdija

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Clinical Trials Mentioned

NCT02119494

Software Mentioned

SPSS
POPE

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