Distribution and characteristics of poststimulus effects in proximal and distal forelimb muscles from red nucleus in the monkey

Journal of Neurophysiology
A Belhaj-SaïfP D Cheney

Abstract

We used stimulus-triggered averaging (StTA) of electromyographic (EMG) activity to investigate two major questions concerning the functional organization of the magnocellular red nucleus (RNm) for reaching movements in the macaque monkey. The first is whether the clear preference toward facilitation of extensor muscles we have reported in previous studies for distal (wrist and digit) forelimb muscles also exists for proximal muscles (shoulder and elbow). The second question is whether distal and proximal muscles may be cofacilitated from RNm suggesting the representation of functional muscle synergies for coordinated reaching movements. Two monkeys were trained to perform a prehension task requiring multijoint coordination of the forelimb. EMG activity was recorded from 24 forelimb muscles including 5 shoulder, 7 elbow, 5 wrist, 5 digit, and 2 intrinsic hand muscles. Microstimulation (20 microA at 20 Hz) was delivered throughout the movement task. From 137 microstimulation sites in the RNm, a total of 977 poststimulus effects was obtained including 733 poststimulus facilitation effects (PStF) and 244 poststimulus suppression effects (PStS). Of the PStF effects, 58% were obtained from distal muscles; 42% from proximal muscles. D...Continue Reading

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Citations

Jan 11, 2002·Journal of Neurophysiology·K M HornA R Gibson
Apr 2, 2005·Nature Reviews. Neuroscience·Richard Apps, Martin Garwicz
Dec 28, 2007·Journal of Neurophysiology·D M GriffinP D Cheney
Jun 20, 2008·Journal of Neurophysiology·Carlo J De LucaAlexander Adam
Nov 24, 2012·Journal of Neurophysiology·Sasha B GodfreyMichelle L Harris-Love
Sep 29, 2012·Journal of Neurophysiology·Douglas A KeenAndrew J Fuglevand
May 23, 2019·Nature Communications·Giorgio RizziKelly R Tan
Apr 2, 2004·Journal of Neurophysiology·D B Debicki, P L Gribble
Mar 24, 2016·Neural Plasticity·E B PlowA G Machado
Mar 31, 2017·Journal of Neurophysiology·Heather M HudsonPaul D Cheney
Nov 24, 1999·Journal of Neurophysiology·P L Gribble, D J Ostry
May 3, 2002·The Journal of Physiology·Martin GarwiczJens Schouenborg
Apr 4, 2002·Journal of Neurophysiology·Carlo J De Luca, Zeynep Erim
Apr 2, 2010·Journal of Neurophysiology·Ilana NiskyAmir Karniel
Jan 12, 2008·The Journal of Physiology·Demetris S Soteropoulos, Stuart N Baker
Sep 3, 2016·Journal of Motor Behavior·Shashwati Geed, Peter L E van Kan
Mar 6, 2002·Journal of Neurophysiology·Peter L E Van Kan, Martha L McCurdy
May 28, 2004·Journal of Neurophysiology·Michael C ParkPaul D Cheney
Jan 15, 2014·The Cerebellum·M LefrancP Krystkowiak
Nov 13, 2020·Brain Structure & Function·Gianpaolo Antonio BasileAlberto Cacciola
Mar 23, 2021·Experimental Brain Research·Shashwati GeedAlexander W Dromerick

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