Distribution and correlates of serum 25-hydroxyvitamin D levels in a sample of patients with hip fracture

The American Journal of Geriatric Pharmacotherapy
Carl F PieperKenneth W Lyles

Abstract

Vitamin D deficiency is common in older populations, particularly during the winter months due to low levels of ultraviolet light exposure, and in nursing home residents. The main objective of the current study was to assess the distribution of serum 25-hydroxyvitamin D and its correlates in a sample of men and women with recent hip fractures who were part of a large clinical trial. This was a cross-sectional exploratory study of screened and ultimately randomized patients with hip fractures. They were part of a multinational (115 clinical centers in 20 countries), randomized, placebo-controlled, double-blind study testing the efficacy of a yearly IV bisphosphonate (zoledronic acid) in the prevention of new clinical fractures in patients with recent hip fracture repair. Levels of 25-hydroxyvitamin D, calcium, alkaline phosphatase, creatinine clearance, and albumin were measured at a screening visit using blood serum. Demographic variables were assessed by patient self-report. Bone mineral density (BMD) was assessed by dual-energy x-ray absorptiometry of the nonfractured hip. This report included 1174 screened patients (526 with vitamin D measured) and 655 (385 with vitamin D measured) patients randomized before the protocol ame...Continue Reading

References

Jan 1, 1976·Nephron·D W Cockcroft, M H Gault
May 5, 1999·JAMA : the Journal of the American Medical Association·M S LeBoffJ Glowacki
Jan 11, 2003·Arthritis and Rheumatism·J Timothy HarringtonDavid A Shewmon
Apr 17, 2003·Maturitas·Hervé LilliuPierre J Meunier
Jul 12, 2003·BMJ : British Medical Journal·Anthony D Woolf, Kristina Akesson
Aug 21, 2003·Clinical Chemistry·Ursula TurpeinenUlf-Håkan Stenman
Oct 22, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Sachin BahlSusan L Greenspan
Nov 7, 2003·The Journal of Clinical Endocrinology and Metabolism·Giovanni PasseriClaudio Franceschi
Apr 20, 2004·The American Journal of Medicine·Heike A Bischoff-FerrariBess Dawson-Hughes
Jun 18, 2004·Current Medical Research and Opinion·Cathleen S Colón-EmericUNKNOWN HORIZON Recurrent Fracture Trial
Jul 9, 2004·The Journal of Clinical Endocrinology and Metabolism·N BinkleyM K Drezner
Jul 12, 2005·Current Medical Research and Opinion·Christine SimonelliYa-Ting Chen
Jul 5, 2007·The American Journal of Geriatric Pharmacotherapy·Sunny A LinneburMichael T McDermott

❮ Previous
Next ❯

Citations

Jun 13, 2012·Current Treatment Options in Cardiovascular Medicine·Jacqueline S Danik, Joann E Manson
Dec 17, 2009·International Journal of Endocrinology·Julie GlowackiMeryl S Leboff
Jun 13, 2012·The Journal of Clinical Investigation·Cathleen S Colón-Emeric, Kenneth W Lyles
Oct 24, 2009·Arthritis Research & Therapy·Kenneth G Saag, Piet Geusens
May 13, 2014·BoneKEy Reports·Peter R Ebeling
Feb 16, 2013·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Cemil KayaliSemmi Koyuncu
Jun 5, 2013·The Journal of Nutrition, Health & Aging·M S LeboffJ Magaziner
Apr 30, 2010·Archives of Gerontology and Geriatrics·Olga E DretakisKonstantin Steriopoulos
May 12, 2009·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·E Michael LewieckiPaul D Miller
May 26, 2009·The Nursing Clinics of North America·Barbara Messinger-Rapport, Linda G Dumas
Sep 10, 2014·Journal of Hospital Medicine : an Official Publication of the Society of Hospital Medicine·John R StephensDarren A DeWalt
May 31, 2015·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Theresa MayesRichard J Kagan
Apr 15, 2014·The Cochrane Database of Systematic Reviews·Alison AvenellDianne O'Connell
Aug 14, 2021·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Antonios A KoutalosTheofilos Karachalios

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JAMA : the Journal of the American Medical Association
Meryl S LeBoffJ Glowacki
Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Meryl S LeBoffJ Magaziner
© 2021 Meta ULC. All rights reserved