Distribution and coverage of A- and B-type horizontal cells stained with Neurobiotin in the rabbit retina

Visual Neuroscience
S L Mills, S C Massey

Abstract

Both A- and B-type horizontal cells in the rabbit retina were labeled by brief in vitro incubations of the isolated retina in the blue fluorescent dye 4,6-diamino-2-phenylindole. Intracellular injection of Lucifer Yellow into the somata revealed the morphology of the individual cells. Dye-coupling with Lucifer Yellow was seen only between A-type horizontal cells. By contrast, injection of the tracer Neurobiotin showed dye-coupling between both A- and B-type horizontal cells. There also appeared to be coupling between the axon terminals of B-type horizontal cells. The extensive dye-coupling seen following injection of Neurobiotin into a single horizontal cell soma can be used to obtain population counts of each cell type. Staining of large numbers of each cell type across the retina showed that each type increased in number and declined in dendritic diameter as the visual streak was approached, such that relatively constant coverage across the retina was maintained. In the visual streak, A-type horizontal cells numbered 555 cells/mm2 and averaged 120 microns in diameter, compared to 1375 cells/mm2 and 100 microns for B-type horizontal cells. In the periphery, the A- and B-types numbered 250 cells/mm2 and 400 cells/mm2, respectiv...Continue Reading

References

Mar 22, 1978·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·H Wässle, H J Riemann
Dec 18, 1978·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·B B BoycottH Wässle
Dec 18, 1978·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·H WässleL Peichl
Dec 18, 1978·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·H WässleB B Boycott
Apr 8, 1992·The Journal of Comparative Neurology·H KolbS K Fisher
Jul 1, 1992·The Journal of Comparative Neurology·S L Mills, S C Massey
Feb 15, 1991·The Journal of Comparative Neurology·S L Mills, S C Massey
Jul 1, 1991·Visual Neuroscience·D I VaneyI C Gynther
Jun 22, 1985·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·D I Vaney
Jan 22, 1987·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·B B BoycottH G Sperling
May 1, 1988·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J H Sandell, R H Masland
Feb 8, 1988·The Journal of Comparative Neurology·K A Linberg, S K Fisher
Jul 1, 1969·Archives of Ophthalmology·F M Honrubia, J H Elliott
Jan 1, 1971·Vision Research·A Gallego
Sep 30, 1966·Science·J E DowlingD Major
Nov 22, 1984·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R H MaslandS A Hayden
Feb 22, 1984·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·D I Vaney
Jul 1, 1982·The Journal of Comparative Neurology·S A Bloomfield, R F Miller
Jan 1, 1980·The Journal of Comparative Neurology·H KolbA Gallego
Oct 1, 1981·Journal of Neurochemistry·A Ames, F B Nesbett
May 22, 1993·Proceedings. Biological Sciences·D I Vaney
Sep 1, 1989·The European Journal of Neuroscience·Jürgen RöhrenbeckBrian B. Boycott
Sep 1, 1989·The European Journal of Neuroscience·H. WässleJ. Röhrenbeck
May 7, 1970·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·H Kolb

❮ Previous
Next ❯

Citations

Apr 10, 1995·The Journal of Comparative Neurology·R ScheibeA Reichenbach
Jul 14, 1997·The Journal of Comparative Neurology·D Xin, S A Bloomfield
Dec 21, 2006·The Journal of Comparative Neurology·Feng Pan, Stephen C Massey
Feb 26, 1996·The Journal of Comparative Neurology·S C Massey, S L Mills
Jun 26, 1999·The European Journal of Neuroscience·I Hack, L Peichl
Dec 19, 2003·Cell Communication & Adhesion·Stephen C MasseyJohn O'Brien
Jul 26, 2006·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Hideo HoshiStephen L Mills
Jun 16, 2010·PloS One·Christophe Ribelayga, Stuart C Mangel
Mar 9, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·P K AhneltA Kübber-Heiss
Aug 15, 2001·The Journal of Comparative Neurology·E B TrexlerS C Massey
Dec 15, 2004·Visual Neuroscience·Michael KalloniatisHeinz Wässle
Feb 14, 2006·Visual Neuroscience·S M A de LimaL C L Silveira
Aug 23, 2007·Visual Neuroscience·Feng PanStephen C Massey
Oct 29, 2010·BMC Ophthalmology·Goran SöhlKlaus Willecke
Mar 16, 2000·The Journal of Physiology·S A Bloomfield, D Xin
Jan 19, 2016·Frontiers in Molecular Neuroscience·Mu Qiao, Joshua R Sanes
Feb 5, 1996·The Journal of Comparative Neurology·K A LinbergS K Fisher
Apr 13, 2012·The Journal of Comparative Neurology·Feng PanStephen C Massey

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.