Distribution and MK-801-induced expression of serine racemase mRNA in rat brain by real-time quantitative PCR

Brain Research. Molecular Brain Research
Masanobu YoshikawaAtsushi Hashimoto

Abstract

We have used real-time quantitative PCR methods to evaluate the effect of the systemic administration of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801; 0.4 mg/kg) on the gene expression of serine racemase in several brain areas of the rat. The levels of serine racemase mRNA in all the brain areas transiently increased after the administration. The present findings suggest that there is a link between the expression of serine racemase mRNA and the activity of the NMDA receptors.

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Citations

Oct 24, 2007·Molecular Neurobiology·Herman Wolosker
Mar 18, 2006·Neuron Glia Biology·Asif K MustafaSolomon H Snyder
Sep 11, 2007·Archives of Histology and Cytology·Masanobu YoshikawaSetsuko Noda
Nov 1, 2008·Archives of Histology and Cytology·Naoko TakayasuSetsuko Noda
Mar 19, 2009·European Journal of Pharmacology·Yasuhiro KosugeTakayuki Sakai
May 2, 2008·European Journal of Pharmacology·Atsushi HashimotoHiroyuki Kobayashi
Nov 9, 2004·Brain Research. Molecular Brain Research·Masanobu YoshikawaAtsushi Hashimoto
Sep 16, 2006·European Journal of Pharmacology·Masanobu YoshikawaAtsushi Hashimoto
May 24, 2006·European Journal of Pharmacology·Kazuhide TakeyamaAtsushi Hashimoto
Nov 18, 2005·European Journal of Pharmacology·Atsushi Hashimoto, Masanobu Yoshikawa
Nov 1, 2005·European Journal of Pharmacology·Masanobu YoshikawaAtsushi Hashimoto
Jul 14, 2006·Neuroreport·Amy E SteffekJames H Meador-Woodruff
Aug 15, 2014·American Journal of Alzheimer's Disease and Other Dementias·Jing YangYawei Kong
Sep 21, 2007·The European Journal of Neuroscience·Louise VerrallPhilip W J Burnet
Sep 13, 2014·The Bulletin of Tokyo Dental College·Takashi ShinomiyaMasanobu Yoshikawa

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