Journal of Wildlife Diseases
Cristina FevolaHeidi C Hauffe


Ljungan virus (LV) is a picornavirus originally isolated from Swedish bank voles ( Myodes glareolus ) in 1998. The association of LV with human disease has been debated ever since, but fundamental data on the ecology of the virus are still lacking. Here we present results of the first intensive study on the prevalence of LV in bank voles trapped in Fennoscandia (Sweden and Finland) from 2009-12 as determined by PCR. Using an LV-specific real-time reverse transcriptase PCR, LV was detected in the liver of 73 out of 452 (16.2%) individuals and in 13 out of 17 sampling sites across Sweden and Finland (mean per site prevalence 16%, SE 3%, range 0-50%). We found more infected animals in autumn compared to spring, and lighter and heavier individuals had a higher prevalence than those with intermediate body masses. The result that LV prevalence is also lower in heavier (i.e., older) animals suggests for the first time that LV infection is not persistent in rodents.


Jan 1, 1986·Archives of Virology·R VerhagenG van der Groen
Mar 26, 2003·The Journal of General Virology·E Susanne JohanssonA Michael Lindberg
May 15, 2003·International Journal of Experimental Diabesity Research·Bo NiklassonÅke Lernmark
Oct 3, 2003·The Lancet Infectious Diseases·Olli VapalahtiA Vaheri
Jan 14, 2004·Emerging Infectious Diseases·Paula M PelkonenOlli Vapalahti
Aug 9, 2006·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Annika SamsioeBo Niklasson
Oct 10, 2006·Pathologie-biologie·Denis AugotF Cliquet
Feb 22, 2007·Journal of Medical Virology·Sisko TauriainenHeikki Hyöty
Aug 21, 2008·Journal of Medical Virology·German TapiaKjersti S Rønningen
Jun 6, 2009·Vector Borne and Zoonotic Diseases·Sandra EssbauerMartin Pfeffer
Jul 2, 2010·Proceedings. Biological Sciences·Eva R KallioOlli Vapalahti
Aug 28, 2010·Vector Borne and Zoonotic Diseases·Gert E OlssonHeikki Henttonen
May 15, 2013·Archives of Virology·Anne-Marie SalisburyJames P Stewart
Jul 16, 2013·Journal of Medical Virology·Anne J JääskeläinenOlli Vapalahti
Sep 11, 2013·Nature Reviews. Microbiology·Antti VaheriJukka Mustonen
Dec 18, 2013·Ecology and Evolution·Magnus MagnussonB Hörnfeldt
Apr 3, 2014·Vector Borne and Zoonotic Diseases·Kristian M ForbesOtso Huitu
Feb 19, 2016·Scientific Reports·Liina VoutilainenHeikki Henttonen


Jun 4, 2020·Vector Borne and Zoonotic Diseases·Cristina FevolaHeidi C Hauffe

Methods Mentioned


Related Concepts

Picornaviridae Infections
Family Picornaviridae
Polymerase Chain Reaction
Virus Diseases

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