Distribution of adrenergic receptors in the domestic fowl oviduct

Poultry Science
J CrossleyH Eiler

Abstract

The effect of epinephrine, phenoxybenzamine (alpha-receptor blocker), and propranolol (beta-receptor blocker) on the oviductal motility in an in vitro system was investigated in strips from infundibulum, magnum, isthmus, and uterus from laying hens. Epinephrine resulted in a significant (P less than .05) contraction of both infundibulum (+166.6%) and magnum (+70.3%) and relaxation of the uterus (-56.9%), while the response of the isthmus was inconsistent. Epinephrine induced contractions in propranolol blocked strips in all four oviductal segments studied (infundibulum, +138.1; magnum, +70.4; isthmus, +35.9; and uterus, +30.1%). Epinephrine, in phenoxybenzamine-blocked strips, resulted in relaxation of all segments (infundibulum, -27.5; magnum, -40.5; isthmus, -63.4; and uterus -53.6%). These results suggest that the activity of alpha-excitatory adrenergic receptors is greater in the anterior than in the posterior segment of the oviduct. conversely, greater activity of beta-inhibitory receptors seems to be present in the posterior than in the anterior segment of the oviduct.

Citations

Jan 1, 1984·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·N G Zimmermann, C G Scanes
Jan 1, 1985·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·S J IturriA Torres
Sep 1, 1989·British Journal of Pharmacology·F M AbdallaB C Prezoto

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.