Distribution of bioactive factors in human milk samples

International Breastfeeding Journal
Reka A VassAndrea Tamas

Abstract

Breast milk provides nutrition for infants and also contains a variety of bioactive factors that influence the development of the newborn. Human milk is a complex biological fluid that can be separated into different layers (water phase and lipid phase with its component water and lipid fractions). It can affect the developing human body along the whole length of the gastrointestinal tract, and through the circulation, its factors may reach every organ. In the present study, we analyzed milk samples collected monthly for 6 months from 16 mothers from the 4th week postpartum between 2014 and 2016 in Baranya County, Hungary. The 96 samples provided us information about the fluctuation of certain bioactive factors during the first 6 months of lactation. We investigated with Luminex technology the concentrations of several cytokines (CD40, Flt-3L), chemokines (MCP-1, RANTES, GRO, MIP-1ß, MDC, eotaxin, fractalkine), and epidermal growth factor (EGF). Paired t-tests and one-way ANOVA followed by Bonferroni post-hoc tests were used to compare the data. We detected the presence of each bioactive factor in every layer of the milk samples during the first 6 months of breastfeeding in widespread concentration ranges. In the case of GRO, M...Continue Reading

References

Oct 31, 1975·Biochimica Et Biophysica Acta·S Patton, T W Keenan
Jul 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·S D CushingA M Fogelman
May 1, 1990·The Journal of Experimental Medicine·B MoserM Baggiolini
Feb 1, 1984·Pediatric Research·L C ReadF J Ballard
Mar 1, 1984·Archives of Disease in Childhood·L T WeaverR Nelson
Mar 1, 1996·Gut·R J Playford, N A Wright
Jan 1, 1996·Rapid Communications in Mass Spectrometry : RCM·S CatinellaR Marsilio
May 17, 2000·Pediatric Research·M F BöttcherR P Garofalo
Oct 4, 2000·Physiological Reviews·J Pácha
Apr 5, 2001·Trends in Immunology·V Appay, S L Rowland-Jones
Sep 24, 2004·Advances in Experimental Medicine and Biology·Bohuslav DvorakRichard J Schanler
Mar 22, 2005·Current Pharmaceutical Design·William A Banks
Jun 24, 2006·Clinical and Experimental Immunology·T SpoettlG Rogler
Jan 11, 2007·Pediatric Research·David S Newburg, W Allan Walker
Mar 17, 2007·Clinical Chemistry·Miloslav KverkaHelena Tlaskalova-Hogenova
Oct 2, 2007·Breastfeeding Medicine : the Official Journal of the Academy of Breastfeeding Medicine·Rose BosireCarey Farquhar
Mar 12, 2008·Clinical Reviews in Allergy & Immunology·Carol L WagnerDonna Johnson
Feb 12, 2009·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Maureen W Groër, Melissa M Shelton
Nov 12, 2009·BioFactors·Antonios ChatzigeorgiouElli Kamper
Jan 20, 2011·The Journal of Comparative Neurology·Jocelyne BlochJean-François Brunet
Jun 9, 2012·Journal of Proteome Research·Xinliu GaoQiang Zhang
Nov 28, 2012·Pediatric Clinics of North America·Olivia Ballard, Ardythe L Morrow
Jun 5, 2013·Laboratory Investigation; a Journal of Technical Methods and Pathology·Makito MiyakeCharles J Rosser
Oct 11, 2013·Frontiers in Integrative Neuroscience·Augusto J Montiel-CastroGustavo Pacheco-López
Apr 8, 2014·The Journal of Pharmacology and Experimental Therapeutics·Michelle A EricksonWilliam A Banks
Aug 7, 2014·International Breastfeeding Journal·Nemat HajeebhoyLan Tran Mai
Aug 28, 2014·Frontiers in Cellular Neuroscience·Graham K SheridanKeith J Murphy
Feb 26, 2015·Journal of Pediatric Gastroenterology and Nutrition·Niklas TimbyMagnus Domellöf
Jan 2, 2016·The Journal of Biological Chemistry·Krishna Mohan Sepuru, Krishna Rajarathnam
Feb 11, 2016·Inflammatory Bowel Diseases·Mei Lan Chen, Mark S Sundrud
Jun 15, 2017·Frontiers in Immunology·Nicole Theresa Cacho, Robert M Lawrence

❮ Previous
Next ❯

Citations

Jan 31, 2020·Pediatric Research·Réka A VassRobert D Roghair
Feb 15, 2020·American Journal of Human Biology : the Official Journal of the Human Biology Council·Duaa KuziezElizabeth A Quinn
Apr 15, 2020·Nutrients·Katríona E LyonsCatherine Stanton
Jun 13, 2019·Nutrients·Andrea Gila-DiazDavid Ramiro-Cortijo
Jul 23, 2021·Plant Foods for Human Nutrition·Soon Hong Kwan, Puteri Shafinaz Abdul-Rahman

❮ Previous
Next ❯

Software Mentioned

SPSS Statistics
RANTES
xPonent

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.