PMID: 6168760Sep 1, 1981Paper

Distribution of bovine fetuin and albumin in plasma, allantoic and amniotic fluids during development

Journal of Reproduction and Fertility
P C LaiF L Lorscheider

Abstract

A radioimmunoassay for bovine fetuin was developed and its specificity and validity established. Albumin was measured by radial-immunodiffusion assay. Fetuin levels in fetal plasma increased from 10 to 15 mg/ml between 4 and 8 months of gestation; albumin levels remained higher than fetuin. Neonatal plasma fetuin levels rapidly declined during the first 14 days post partum, coincident with a marked reciprocal increase in albumin levels. In allantoic fluid fetuin and albumin concentrations reached a peak at 7 months but fetuin values were always higher. In amniotic fluid both proteins peaked at 8 months; albumin levels were similar to those in allantoic fluid but fetuin values remained consistently lower than those in allantoic fluid throughout gestation. Fetuin levels in maternal plasma declined from 0.7 to 0.4 mg/ml between 1 month and term. We conclude that (1) at term there is an abrupt change from fetuin synthesis to increased albumin synthesis by the neonatal liver; (2) fetuin appears to be preferentially accumulated in the allantois whereas albumin is equally concentrated in the allantois and amnion.

Citations

Jul 26, 1982·Biochimica Et Biophysica Acta·D E Panrucker, F L Lorscheider
Jan 1, 1984·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·P McKenna
Jan 1, 1997·Life Sciences·S T MathewsG Grunberger
Jan 15, 2014·Acta Veterinaria Scandinavica·Mathilde BériotNoelita M de Sousa
Nov 11, 2016·Science Translational Medicine·Lydia L ShookIrina A Buhimschi
Dec 25, 2017·Journal of Dairy Science·Clarissa Strieder-BarbozaG Andres Contreras
Jun 1, 1986·Journal of Cellular Physiology·M AbdullahA L Kierszenbaum

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