Abstract
Streptococcus pneumoniae (SPN) is the most common cause of invasive infections in children, with high levels of mortality in developing countries. An increase in frequency of penicillin-resistant strains is reported in most parts of the world. A study was undertaken in Argentina and 5 other countries of the region, to determine the type distribution and penicillin resistance rate of SPN isolated from invasive infections in children less than 5 years old. Between June 1994 and March 1996, a total of 505 SPN isolated from sterile sites were collected from 15 hospitals located in 9 cities of different geographic areas. Clinical and epidemiological data from 443 children were analyzed. Sixty five percent SPN were isolated from children less than 2 years old. Pneumonia was the clinical diagnosis in 58% of the cases, meningitis in 22%, and sepsis in 10.6%. Isolates were recovered from blood (51.2%), pleural fluid (22.7%), CSF (20.7%), and other sterile sites (5.4%). Thirty different pneumococcal capsular types were identified and the 10 most frequent in descending order were: 14, 5, 1, 6A/6B, 7F, 9V, 19F, 19A, 16F y 23F, representing 89.3% of the total. Overall, 13.1% of isolates showed intermediate resistance to penicillin while 11....Continue Reading
References
Aug 11, 1992·Antimicrobial Agents and Chemotherapy·E O MasonJ Tillman
Dec 16, 1992·JAMA : the Journal of the American Medical Association·J EskolaM Leinonen
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·P C Appelbaum
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·H J KoornhofK Klugman
Jul 1, 1992·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J LiñaresR Martin
Jan 19, 1991·Lancet·T D MastroR R Facklam
Jan 1, 1991·The Pediatric Infectious Disease Journal·I M ForgieB M Greenwood
Aug 1, 1991·The Journal of Infectious Diseases·R MuñozB G Spratt
Mar 1, 1991·The Journal of Infectious Diseases·A MartonA Tomasz
Jan 1, 1991·The Pediatric Infectious Disease Journal·I M ForgieB M Greenwood
Jan 1, 1991·Reviews of Infectious Diseases·A FenollJ Casal
Apr 1, 1990·Clinical Microbiology Reviews·K P Klugman
Jan 1, 1990·Revista Do Instituto De Medicina Tropical De São Paulo·A E TaunayC E Melles
Mar 1, 1986·Pediatric Infectious Disease·F Shann
Mar 1, 1981·Reviews of Infectious Diseases·R Austrian
May 1, 1995·The Pediatric Infectious Disease Journal·J O Klein
Sep 1, 1994·The Pediatric Infectious Disease Journal·R DaganK Klugman
Oct 1, 1993·The Pediatric Infectious Disease Journal·T D MastroB Schwartz
Jan 1, 1993·Scandinavian Journal of Infectious Diseases·S V Nielsen, J Henrichsen
Oct 1, 1995·The Pediatric Infectious Disease Journal·I R Friedland
Dec 1, 1995·Antimicrobial Agents and Chemotherapy·K M KamM M Cheung
Citations
Sep 7, 2000·Diagnostic Microbiology and Infectious Disease·J SmayevskyA Sucari
Aug 29, 2000·International Journal of Antimicrobial Agents·M R Jacobs, P C Appelbaum
Mar 6, 1999·Current Opinion in Microbiology·J B McCormick
Jan 5, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·W P HausdorffG R Siber
Jul 20, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D FraserR Dagan
Feb 2, 2002·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·M HortalUNKNOWN PAHO SIREVA-Vigía Study Group
Apr 20, 2001·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·B RosónF Gudiol
Nov 18, 1998·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·M C BrandileoneA Tomasz
Sep 3, 1998·The Pediatric Infectious Disease Journal·A ArguedasE Mohs
Oct 20, 2001·The Pediatric Infectious Disease Journal·J L Di FabioC De Quadros
Jul 13, 2004·The Pediatric Infectious Disease Journal·James D CampbellMyron M Levine
Nov 5, 2002·Clinical and Diagnostic Laboratory Immunology·Anna R CullottaM Urbina
Jan 4, 2001·Journal of Clinical Microbiology·F C TenoverR Williams
Nov 1, 2002·Journal of Clinical Microbiology·Liliana GamboaUNKNOWN Sireva-Vigía Working Group
May 30, 2012·BMC Infectious Diseases·Elizabeth CastañedaRómulo E Colindres
Oct 29, 2004·Annals of Clinical Microbiology and Antimicrobials·Rosa Cangemi de GutiérrezMaría Elena Nader-Macías
Aug 30, 2006·Paediatric Respiratory Reviews·Paulo CamargosRaúl Ruvinsky
Dec 24, 2003·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Javier AltclasAna Di Martino
Sep 15, 2015·Journal of Epidemiology and Global Health·Yagob AlmazrouWilliam P Hausdorff
Nov 18, 1998·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·A RossiA Tomasz
Jun 12, 1999·Journal of Clinical Microbiology·M TamayoH de Lencastre