PMID: 420304Feb 1, 1979Paper

Distribution of cardiac output during induced isometric exercise in dogs

The American Journal of Physiology
S C CraytonJ H Mitchell

Abstract

Studies were designed to characterize the distribution of cardiac output during induced isometric exercise in anesthetized dogs. The response to isometric exercise involved significant increases in heart rate (+12 +/- 3%(SE)), mean arterial pressure (+13 +/- 2%), cardiac output (+26 +/- 8%), and respiratory minute volume (+75 +/- 26%); total peripheral resistance did not change significantly. Significant changes in blood flow were observed during isometric exercise in kidneys (-18 +/- 6%) and contracting limb muscles (+453 +/- 154%). Flow to liver (hepatic artery), spleen, brain, and myocardium remained near control values. Section of spinal dorsal roots L6-L7 abolished the responses to isometric exercise except for the increase in flow to exercising limb muscles. Alpha-adrenergic receptor blockade abolished the decrease in renal blood flow during isometric exercise; however, the increase in flow to exercising limb muscles was not affected by either alpha- or beta-adrenergic blockade.

Citations

May 17, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Afsana MomenLawrence I Sinoway
Sep 1, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rachel C Drew
Jun 14, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Afsana MomenLawrence I Sinoway
Mar 11, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Afsana MomenLawrence I Sinoway
Dec 25, 2012·Experimental Physiology·Jere H Mitchell
Apr 7, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rachel C DrewLawrence I Sinoway
Sep 1, 1981·Basic Research in Cardiology·J C LonghurstJ H Mitchell
Oct 26, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·J W DanielsJ C Longhurst
Nov 12, 2013·American Journal of Physiology. Heart and Circulatory Physiology·Kazuhito WatanabeTakeshi Nishiyasu
Dec 31, 2016·The Journal of Physiological Sciences : JPS·Ichiro ShojiYasuhiro Nishida

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