Jan 1, 1996

Distribution of cholecystokinin-8-like immunoreactivity in the frog brain and spinal cord

Acta Biologica Hungarica
M Petkó, T Kovács


The distribution of cholecystokinin-8 (CCK8) containing structures in the central nervous system of the frog (Rana esculenta) was investigated with the aid of the peroxidase immunohistochemical method. In the forebrain, immunoreactive perikarya were found in the main olfactory bulb, septum, amygdala, and ventromedial thalamic nuclei. Networks of immunoreactive varicose fibers were observed in the septum, the basal area, and the infundibulum, and fiber bundles were found in the marginal and axial optic tracts. In the midbrain, immunoreactive cell bodies were seen in the mesencephalic reticular nucleus, and networks of fibers were observed in the optic tectum and the tegmentum. In the hindbrain, immunoreactive neurons were found in the nucleus of the solitary tract, and varicose fibers were observed in the superior vestibular nucleus and the subventricular area. The gray matter of the spinal cord was interlaced by immunoreactive fibers, and a few intensely stained perikarya were seen in the base of the dorsal horn. These findings indicate that CCK8 is widely distributed in the central nervous system of the frog, like in mammals. The CCK8 immunoreactivity is particularly high in the limbic structures and some diencephalic and mese...Continue Reading

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Nucleus Solitarius
Optic Tract Structure
Thalamic Nuclei
Structure of Olfactory Bulb
Entire Pallium
Cholecystokinin Measurement

About this Paper

Related Feeds

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.