Distribution of effective synaptic currents in cat triceps surae motoneurons. VI. Contralateral pyramidal tract

Journal of Neurophysiology
M D BinderR K Powers

Abstract

We measured the effective synaptic currents (IN) produced by stimulating the contralateral pyramidal tract (PT) in triceps surae motoneurons of the cat. This is an oligosynaptic pathway in the cat that generates both excitation and inhibition in hindlimb motoneurons. We also determined the effect of the PT synaptic input on the discharge rate of some of the motoneurons by inducing repetitive firing with long, injected current pulses during which the PT stimulation was repeated. At resting potential, all but one triceps motoneuron received a net depolarizing effective synaptic current from the PT stimulation. The effective synaptic currents (IN) were much larger in putative type F motoneurons than in putative type S motoneurons [+4.6 +/- 2.9 (SD) nA for type F vs. 0.9 +/- 2.4 nA for putative type S]. When the values of IN at the threshold for repetitive firing were estimated, the distribution was markedly altered. More than 60% of the putative type S motoneurons received a net hyperpolarizing effective synaptic current from the pyramidal tract stimulation as did 33% of the putative type F motoneurons. This distribution pattern is very similar to that observed previously for the effective synaptic currents produced by stimulating...Continue Reading

References

Sep 1, 1992·Journal of Neurophysiology·R K PowersM D Binder
Feb 1, 1985·Journal of Neurophysiology·R K Powers, M D Binder
Dec 1, 1981·Journal of Neurophysiology·J W FleshmanW A Friedman
Sep 1, 1983·The Journal of Physiology·A S Finkel, S J Redman
Aug 1, 1995·Journal of Neurophysiology·R K Powers, M D Binder
Oct 1, 1993·Journal of Neurophysiology·R K PowersM D Binder
Apr 1, 1993·Journal of Neurophysiology·C J Heckman, M D Binder
Jan 1, 1995·Experimental Brain Research·S L WestcottM D Binder
Nov 28, 1955·The Journal of Physiology·J S COOMBSP FATT

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Citations

Jun 13, 2003·Journal of Neurophysiology·Angel M Pastor, David Gonzalez-Forero
Aug 8, 2019·Journal of Neurophysiology·Sabhya RanaGary C Sieck
Jan 15, 2000·Journal of Neurophysiology·R K Powers, M D Binder
Oct 3, 2002·The Journal of Physiology·Nicolas T PetersenSimon C Gandevia
Oct 3, 2001·Physiological Reviews·S C Gandevia
Feb 13, 2007·Nature Neuroscience·Allison S HyngstromC J Heckman
Feb 19, 2016·Physiology·Dario FarinaRoger M Enoka
Feb 2, 2008·The Journal of Physiology·Allison HyngstromC J Heckman
Sep 8, 2019·Experimental Brain Research·J B NielsenH Hultborn
Sep 10, 2011·Neurorehabilitation and Neural Repair·Inge ZijdewindChristine K Thomas
Dec 6, 2014·Journal of Neurophysiology·Andrew J FuglevandRichard K Johns
Apr 27, 2021·Frontiers in Neuroscience·Andrew E MontgomerySherif M Elbasiouny
Mar 1, 2005·Muscle & Nerve·C J HeckmannDavid J Bennett

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