Distribution of four capsular serotypes of Enterococcus faecalis among clinical isolates from different geographical origins and infection sites

Infection
M HufnagelJohannes Huebner

Abstract

Enterococci possess capsular polysaccharide antigens that are the targets of opsonic antibodies. These antibodies are potential candidates for development as immunotherapy. The present study analyzes the distribution of four capsular serotypes within a collection of 157 isolates of Enterococcus faecalis from four countries with different sites of clinical infection. By using a capsular polysaccharide-specific ELISA, 42% of the isolates were grouped into one of four serogroups, and another 9% showed cross-reactivity between two serotype-specific sera. Heterogeneity of serotype distribution by both geographical origin and infection site was observed. Half of the strain collection could be typed with four serotype-specific sera. No serotype from a given country or infection site clearly predominated.

Citations

Jun 24, 2009·The Journal of Infectious Diseases·Kavindra V SinghBarbara E Murray
Mar 17, 2018·FEMS Microbiology Reviews·Francesca MicoliRoberto Adamo
Nov 6, 2020·Cells·Ermioni Kalfopoulou, Johannes Huebner

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